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Hdac6 (BC041105) Mouse Tagged ORF Clone

  • TrueORF®
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SKU
MR211715
Hdac6 (Myc-DDK-tagged) - Mouse histone deacetylase 6 (cDNA clone MGC:46887 IMAGE:5352032)
Interest in protein/lysate? Submit request here!
ORF Plasmid:
DDK tGFP
Lentiviral Particles:
DDK w/ Puro mGFP w/ Puro
$589.00 $1,003.00
In Stock*
Bulk Requests & Clone Modifications

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Specifications
Specifications
Product Data
Type Mouse Tagged ORF Clone
Target Symbol Hdac6
Synonyms Hdac5, mHDA2
Vector pCMV6-Entry
E. coli Selection Kanamycin (25 ug/mL)
Mammalian Cell Selection Neomycin
Sequence Data
ORF Nucleotide Sequence
>MR211715 representing BC041105
Red=Cloning site Blue=ORF Green=Tags(s)

TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
GCCGCGATCGCC

ATGACCTCCACCGGCCAAGATTCTTCTACTAGACAGCGAAAGAGTAGGCACAATCCCCAGTCACCCCTTC
AGGAATCCAGCGCCACCTTGAAGCGTGGTGGAAAGAAGTGTGCTGTACCCCACTCCAGCCCCAATCTAGC
GGAGGTAAAGAAGAAAGGCAAAATGAAGAAGCTGAGCCAACCAGCTGAAGAGGACCTAGTTGTGGGGCTT
CAAGGGCTGGATCTGAACCCTGAGACAAGAGTGCCAGTTGGTACTGGATTGGTGTTTGATGAACAACTAA
ATGACTTCCATTGCCTTTGGGATGACAGCTTCCCTGAAAGCCCTGAGCGGCTCCATGCCATCAGAGAGCA
ACTGATCCTGGAGGGCCTCCTGGGCCGCTGTGTGTCCTTTCAGGCCCGGTTCGCTGAGAAGGAGGAGCTG
ATGTTGGTTCACAGCCTGGAATACATTGATCTGATGGAGACAACCCAGTACATGAATGAAGGGGAGCTTC
GAGTACTGGCAGAAACCTATGATTCAGTGTATCTGCATCCGAACTCATATTCCTGTGCCTGCCTGGCTAC
AGGCTCTGTCCTCCGGCTGGTAGATGCACTCATGGGGGCTGAGATTCGGAATGGCATGGCCGTCATCAGG
CCTCCTGGACACCATGCTCAGCACAATCTTATGGATGGGTATTGCATGTTCAACCATCTGGCTGTGGCTG
CCCGCTATGCGCAAAAGAAGCACCGCATTCAGAGGGTTCTCATCGTGGACTGGGATGTGCACCATGGTCA
AGGAACACAGTTCATCTTCGACCAGGACCCCAGTGTCCTTTATTTCTCCATCCACCGATATGAACATGGT
CGCTTCTGGCCCCACCTTAAGGCTTCTAACTGGTCCACTATAGGTTTTGGCCAAGGCCAAGGATATACCA
TCAATGTACCTTGGAACCAGACGGGCATGCGGGACGCTGACTACATTGCTGCTTTCCTGCACATCCTGCT
GCCAGTTGCCTCGGAGTTTCAGCCTCAACTGGTCTTGGTGGCCGCTGGATTTGATGCCCTCCACGGAGAC
CCCAAGTCCCTTCAGGGAGAGATGGCTGCCACGCCAGCAGGATTTGCCCACCTAACCCATTTGCTCATGG
GTTTGGCAGGAGGCAAGTTGATTCTGTCCCTGGAGGGTGGCTATAACCTCCGTGCCCTGGCTAAGGGAGT
CAGTGCTTCACTCCACACCCTTCTTGGAGACCCTTGCCCCATGCTGGAGTCCTGTGTTGTACCTTGTGCA
AGCGCCCAGACTTCCATCTACTGCACTCTAGAAGCCCTTGAACCCTTCTGGGAGGTCCTGGAGAGATCAG
TTGAGACCCAGGAGGAAGATGAAGTGGAAGAAGCCGTGCTAGAAGAGGAGGAGGAGGAAGGTGGCTGGGA
GGCCACTGCACTGCCCATGGATACATGGCCACTGCTCCAGAACCGCACTGGGCTGGTCTATGATGAGAAG
ATGATGAGTCACTGCAACCTCTGGGACAATCATCACCCTGAGACACCTCAGCGCATCTTACGCATCATGT
GTCACCTGGAGGAGGTGGGCCTTGCGGCTCGCTGTCTCATCCTACCTGCTCGGCCTGCCCTGGACTCTGA
GCTCCTTACCTGCCACAGTGCTGAGTACGTGGAGCATCTCCGCACCACAGAAAAGATGAAAACCCGGGAT
CTGCACCGTGAAGGTGCCAACTTTGACTCCATCTACATCTGCCCCAGCACCTTTGCCTGCGCAAAGCTTG
CCACAGGCGCTGCCTGCCGCCTGGTGGAAGCTGTGCTCTCGGGAGAGGTTCTAAATGGCATTGCAGTAGT
GCGCCCTCCAGGACACCACGCGGAGCCAAATGCTGCCTGTGGTTTCTGCTTTTTCAACTCAGTAGCTGTA
GCTGCTCGCCATGCCCAGATCATTGCTGGACGTGCCCTGCGGATCCTAATCGTGGATTGGGATGTTCATC
ATGGTAATGGAACTCAGCACATATTTGAGGATGACCCTAGTGTATTATACGTGTCCCTGCACCGGTATGA
CCGTGGCACTTTCTTCCCCATGGGGGATGAGGGTGCCAGTAGCCAAGTAGGCCGAGATGCAGGTATAGGC
TTCACTGTCAATGTGCCCTGGAATGGGCCCCGCATGGGTGATGCTGATTACCTGGCTGCATGGCATCGTC
TGGTACTTCCCATCGCCTATGAGTTTAACCCAGAACTGGTGCTGATCTCAGCTGGCTTTGATGCTGCACA
AGGGGATCCGCTGGGGGGCTGCCAAGTAACACCGGAGGGTTATGCCCACCTCACCCACCTACTGATGGGC
CTTGCTGGTGGCCGTATTATTCTTATTCTAGAGGGTGGATACAATTTGGCATCTATCTCTGAGTCTATGG
CTGCCTGCACCCATTCCCTCCTTGGAGACCCACCACCCCAGCTTACTTTGCTGCGACCGCCACAGTCAGG
AGCCCTGGTTTCAATCAGTGAGGTCATCCAAGTCCATCGCAAATACTGGCGCAGTTTGCGGTTGATGAAA
ATGGAAGACAAGGAAGAATGCTCTAGTTCTAGGCTTGTCATCAAGAAGTTGCCCCCAACAGCCAGTCCTG
TATCAGCTAAGGAAATGACCACACCGAAAGGAAAGGTTCCTGAAGAAAGCGTGAGGAAGACCATAGCAGC
ACTACCTGGGAAAGAGTCTACTCTAGGCCAGGCTAAATCAAAGATGGCTAAGGCTGTGCTTGCTCAGGGC
CAGTCCTCAGAACAAGCTGCTAAGGGAACTACACTGGATCTGGCTACCTCAAAGGAGACTGTGGGAGGAG
CCACGACGGACCTGTGGGCCTCAGCAGCTGCTCCTGAAAACTTCCCTAACCAGACCACCTCTGTGGAGGC
TTTGGGAGAAACTGAGCCAACGCCTCCAGCCTCGCATACAAACAAGCAGACCACAGGGGCTTCACCTCTG
CAGGGAGTCACGGCTCAGCAGTCCCTACAGCTTGGGGTTCTCAGCACTTTGGAGCTAAGCAGAGAAGCAG
AGGAAGCCCATGATTCTGAGGAGGGCCTGCTAGGGGAAGCCGCTGGAGGTCAGGACATGAACAGCTTGAT
GCTGACACAAGGATTTGGGGACTTTAATACCCAGGATGTATTTTATGCTGTGACCCCACTATCCTGGTGT
CCCCATTTGATGGCAGTATGCCCCATTCCTGCAGCAGGCCTAGATGTGTCCCAACCTTGTAAGACCTGTG
GAACAGTCCAGGAGAACTGGGTGTGTCTGACTTGCTATCAGGTGTACTGCAGTCGCTATGTCAATGCCCA
TATGGTCTGCCACCATGAAGCCTCTGAACACCCGCTGGTCCTCAGCTGTGTTGACCTGTCTACCTGGTGT
TATGTCTGTCAGGCTTATGTCCACCACGAGGATCTCCAAGATGTGAAGAACGCTGCCCACCAGAACAAGT
TTGGGGAGGACATGCCCCACTCACAC

ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
ACAAGGATGACGACGATAAGGTTTAA
Protein Sequence
>MR211715 representing BC041105
Red=Cloning site Green=Tags(s)

MTSTGQDSSTRQRKSRHNPQSPLQESSATLKRGGKKCAVPHSSPNLAEVKKKGKMKKLSQPAEEDLVVGL
QGLDLNPETRVPVGTGLVFDEQLNDFHCLWDDSFPESPERLHAIREQLILEGLLGRCVSFQARFAEKEEL
MLVHSLEYIDLMETTQYMNEGELRVLAETYDSVYLHPNSYSCACLATGSVLRLVDALMGAEIRNGMAVIR
PPGHHAQHNLMDGYCMFNHLAVAARYAQKKHRIQRVLIVDWDVHHGQGTQFIFDQDPSVLYFSIHRYEHG
RFWPHLKASNWSTIGFGQGQGYTINVPWNQTGMRDADYIAAFLHILLPVASEFQPQLVLVAAGFDALHGD
PKSLQGEMAATPAGFAHLTHLLMGLAGGKLILSLEGGYNLRALAKGVSASLHTLLGDPCPMLESCVVPCA
SAQTSIYCTLEALEPFWEVLERSVETQEEDEVEEAVLEEEEEEGGWEATALPMDTWPLLQNRTGLVYDEK
MMSHCNLWDNHHPETPQRILRIMCHLEEVGLAARCLILPARPALDSELLTCHSAEYVEHLRTTEKMKTRD
LHREGANFDSIYICPSTFACAKLATGAACRLVEAVLSGEVLNGIAVVRPPGHHAEPNAACGFCFFNSVAV
AARHAQIIAGRALRILIVDWDVHHGNGTQHIFEDDPSVLYVSLHRYDRGTFFPMGDEGASSQVGRDAGIG
FTVNVPWNGPRMGDADYLAAWHRLVLPIAYEFNPELVLISAGFDAAQGDPLGGCQVTPEGYAHLTHLLMG
LAGGRIILILEGGYNLASISESMAACTHSLLGDPPPQLTLLRPPQSGALVSISEVIQVHRKYWRSLRLMK
MEDKEECSSSRLVIKKLPPTASPVSAKEMTTPKGKVPEESVRKTIAALPGKESTLGQAKSKMAKAVLAQG
QSSEQAAKGTTLDLATSKETVGGATTDLWASAAAPENFPNQTTSVEALGETEPTPPASHTNKQTTGASPL
QGVTAQQSLQLGVLSTLELSREAEEAHDSEEGLLGEAAGGQDMNSLMLTQGFGDFNTQDVFYAVTPLSWC
PHLMAVCPIPAAGLDVSQPCKTCGTVQENWVCLTCYQVYCSRYVNAHMVCHHEASEHPLVLSCVDLSTWC
YVCQAYVHHEDLQDVKNAAHQNKFGEDMPHSH

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Chromatograms Chromatograms
Sequencher program is needed, download here
Restriction Sites SgfI-MluI Cloning Scheme for this gene | Plasmid Map
ACCN BC041105
ORF Size 3456 bp
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution Method 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Shipping Ambient
Reference Data
RefSeq BC041105.1
RefSeq Size 4016 bp
RefSeq ORF 3458 bp
Locus ID 15185
Cytogenetics X 3.58 cM
MW 147.2 kDa
Summary Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes (By similarity). Plays a central role in microtubule-dependent cell motility via deacetylation of tubulin.UniProtKB/Swiss-Prot Function
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"BC041105" in other vectors (3)
SKU Description Size Price
MG211715 Hdac6 (tGFP-tagged) - Mouse histone deacetylase 6 (cDNA clone MGC:46887 IMAGE:5352032) 10 ug
$789.00 $1,203.00
MR211715L3 Lenti ORF clone of Hdac6 (Myc-DDK-tagged) - Mouse histone deacetylase 6 (cDNA clone MGC:46887 IMAGE:5352032) 10 ug
$1,303.00
MR211715L4 Lenti ORF clone of Hdac6 (mGFP-tagged) - Mouse histone deacetylase 6 (cDNA clone MGC:46887 IMAGE:5352032) 10 ug
$1,303.00

Plasmid Map for MR211715

Download sequence for

file-download TXT (FASTA format)

file-download Genbank

Cloning scheme for MR211715
Circular map for MR211715

file-alt Citations

Upregulation of Profilin 2 on HDAC6 overexpression in mouse GC-1 cells and its putative role in germ cell migration in the testis
Verma, Yevate, E et al
Cell Tissue Res (2023)
Cited by 3
AI Summary: OriGene's murine HDAC6 gene plasmid (Cat # MR211715) was used to overexpress HDAC6 in GC-1spg cells, enabling the study of its effect on Profilin 2 expression and potential role in germ cell migration.
Snippet: Murine HDAC6 gene under CMV promoter and with myc/DDK tag in a pCMV plasmid vector was procured (Cat # MR211715;Origene, Maryland). The plasmid was
Showing 1-1 of 1 papers.
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