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Slitrk3 (NM_198864) Mouse Tagged ORF Clone

  • TrueORF®
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SKU
MR211375
Slitrk3 (Myc-DDK-tagged) - Mouse SLIT and NTRK-like family, member 3 (Slitrk3)
Interest in protein/lysate? Submit request here!
ORF Plasmid:
DDK tGFP
Lentiviral Particles:
DDK w/ Puro mGFP w/ Puro
$589.00 $897.00
In Stock*
Bulk Requests & Clone Modifications

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Specifications
Specifications
Product Data
Type Mouse Tagged ORF Clone
Target Symbol Slitrk3
Synonyms ST3
Vector pCMV6-Entry
E. coli Selection Kanamycin (25 ug/mL)
Mammalian Cell Selection Neomycin
Sequence Data
ORF Nucleotide Sequence
>MR211375 representing NM_198864
Red=Cloning site Blue=ORF Green=Tags(s)

TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
GCCGCGATCGCC

ATGATGAAGCCAAGCATAGCTGAAATGCTTCACAGAGGAAGAATGCTGTGGATAATTCTTCTAAGCACAA
TTGCTCTAGGATGGACTACCCCAATTCCCCTGATAGAGGACTCAGAAGAAATAGATGAGCCCTGTTTTGA
TCCATGCTACTGCGAAGTTAAAGAAAGCCTCTTTCACATACATTGTGACAGCAAGGGATTTACAAACATT
AGTCAGATTACTGAGTTCTGGTCAAGACCTTTTAAACTGTATCTTCAGAGGAATTCGATGAGAAGACTAT
ACACAAACAGTTTTCTTCACTTGAATAATGCGGTGTCCATTAACCTTGGGAACAATGCATTGCAGGACAT
TCAAACTGGAGCATTTAATGGCCTTAAGATTTTAAAGAGACTGTATCTCCATGAGAACAAACTAGATGTC
TTCAGAAATGACACCTTCCTTGGCTTAGAAAGTCTGGAATATCTTCAGGCAGATTACAATGTCATTAAAC
GTATAGAGAGTGGGGCATTTCGGAACCTAAGTAAATTGAGGGTTCTAATCTTAAATGATAATCTCATCCC
CGTGCTTCCAACCAATTTATTTAAAGCTGTTTCCTTAACGCATCTGGACCTTCGTGGGAACAGGTTAAAG
GTTCTCTTCTACCGTGGGATGCTGGATCACATTGGCAGAAGCCTGATGGAGCTCCAGCTAGAAGAGAATC
CTTGGAACTGTACCTGTGAGATAGTACAGCTGAAGAGTTGGCTGGAGCGAATACCTTACACAGCCCTGGT
GGGAGACATTACCTGTGAGACACCTTTCCATTTCCATGGGAAGGATCTCCGTGAAATCAAGAAGACTGAA
CTCTGTCCACTGTTGTCTGACTCTGAGGTGGAGGCCAGTCTGGGGATTCCCCACTTATCTTCAAGCAAGG
AGAATGCCTGGCCAACTAAACCTTCCTCTATGTTGTCTTCTGTCCATTTTACTGCTTCATCTGTTGAATA
TAAGTCCTCTAATAAGCAACCAAAACCCACCAAACAGCCCAGAACACCGAGACCACCTTCGACATCCCAG
GCTTTATATCCTGGTCCAAATCAACCTCCTATTGCCCCCTATCAGACTAGACCACCCATTCCCATTATAT
GTCCTACTGGGTGTACATGCAATTTGCATATCAATGACCTTGGCTTGACTGTCAACTGCAAAGAAAGAGG
ATTTAACAACATCTCTGAACTCCTTCCAAGGCCCTTGAATGCCAAGAAGCTGTACCTGAGCAGCAATCTT
ATTCAGAAGATATACCGCTCTGATTTTTGGAATTTTTCTTCTTTGGATCTCTTGCACCTAGGGAACAATC
GCATTTCCTACGTCCAGGATGGGGCTTTCATCAACCTGCCCAACCTGAAGAGTCTCTTTCTCAATGGCAA
TGATATAGAAAAGCTGACTCCAGGTATGTTCCGAGGTCTGCAGAGCTTGCATTACTTGTACTTCGAATTC
AACGTCATCCGGGAAATCCAACCTGCAGCCTTCAGCCTCATGCCCAACTTGAAGCTGCTATTTCTCAACA
ATAACTTGCTGAGGACTCTGCCAACTGATGCCTTTGCAGGTACATCCCTGGCTCGGCTCAACTTGAGGAA
GAACTACTTTCTCTACCTGCCAGTGGCTGGTGTCCTTGAACACCTGAATGCCATTGTGCAGATAGATCTC
AACGAGAATCCTTGGGACTGCACTTGCGACTTAGTCCCCTTTAAGCAGTGGATCGAAACCATCAGCTCAG
TCAGCGTGGTAGGTGATGTACTCTGTAGGACCCCCGAGAACCTCACCCACCGTGATGTGCGCACTATTGA
GCTGGAAGTTTTATGCCCAGAGATGCTGCATATTGCCCAACCTGGACCATCTCCACCCCAGCCTGGAGAT
TACCACCCTAACGGGGGACCAACAAGTGCATCACCTTATGAGTTCTCTCCCCCAGGGGGCCCTGTGCCAC
TTTCTGTGTTGATTCTCAGCCTCTTGGTTCTGTTCTTCTCAGCTGTCTTTGTTGCTGCAGGCCTCTTTGC
CTATGTGCTCCGTCGGCGTAGGAAGAAGTTGCCCTTTAGAAGCAAGAGACAAGAAGGTGTGGACCTTACA
GGAATCCAGATGCAATGTCACCGGCTGTTTGAGGACAGTGGAGGCAACAGTGGTGGGAGTGGAGGTGGAG
GGCGACCAACTCTGTCCTCGCCAGAGAAAGCCCCTCCCGTGGGTCACGTGTACGAGTATATACCCCACCC
AGTAACTCAGATGTGTAACAACCCCATCTATAAGCCTCGAGAGGAGGAAGAAGTGGCTGCCTCAGCAGCC
CAGGACACAGGAGCTACAGACCGTGGAGGTCCTGGTACACAACCAACAGGAATGGCTGAGGTGCTCTTGG
GAAGTGAGCAGTTTGCAGAAACACCCAAGGAGAACCACAGTAACTACAGGACCTTGCTGGAAAAAGAGAA
GGAGTGGGCTCTGGCTGTTTCCAACTCTCAACTTAACACCATAGTGACGGTGAACCATCACCACCCTCAC
CCTCACCACTCGGCAGTTGGTGGGGTTTCAGGGGTAGGTGGAGGGACTGGGGGAGACTTGGCTGGGTTCC
GCCACCATGAGAAGAATGGTGGGGTGGTGCTGTTTCCCCCTGGGGGAGGTTGTGGTGGTGGCAGTCTGCT
ACTAGACCGTGAGAGGCCACAGCCTGCTCCGTGCACAGTGGGATTTGTGGACTGTCTCTATGGCACAGTG
CCCAAATTAAAGGAACTCCATGTCCACCCCCCTGGCATGCAATATCCAGACTTACAGCAGGATGCCAGGC
TCAAAGAAACCCTTCTCTTCTCAGCTGGAAAGGGCTTCACAGACCACCAAACCCCCAAAAGTGATTACCT
CGACTTAAGGGCCAAACTTCAAACTAAGCCGGATTACCTCGAAGTTCTGGAGAAAACAGCATACAGGTTC

ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
ACAAGGATGACGACGATAAGGTTTAA
Protein Sequence
>MR211375 representing NM_198864
Red=Cloning site Green=Tags(s)

MMKPSIAEMLHRGRMLWIILLSTIALGWTTPIPLIEDSEEIDEPCFDPCYCEVKESLFHIHCDSKGFTNI
SQITEFWSRPFKLYLQRNSMRRLYTNSFLHLNNAVSINLGNNALQDIQTGAFNGLKILKRLYLHENKLDV
FRNDTFLGLESLEYLQADYNVIKRIESGAFRNLSKLRVLILNDNLIPVLPTNLFKAVSLTHLDLRGNRLK
VLFYRGMLDHIGRSLMELQLEENPWNCTCEIVQLKSWLERIPYTALVGDITCETPFHFHGKDLREIKKTE
LCPLLSDSEVEASLGIPHLSSSKENAWPTKPSSMLSSVHFTASSVEYKSSNKQPKPTKQPRTPRPPSTSQ
ALYPGPNQPPIAPYQTRPPIPIICPTGCTCNLHINDLGLTVNCKERGFNNISELLPRPLNAKKLYLSSNL
IQKIYRSDFWNFSSLDLLHLGNNRISYVQDGAFINLPNLKSLFLNGNDIEKLTPGMFRGLQSLHYLYFEF
NVIREIQPAAFSLMPNLKLLFLNNNLLRTLPTDAFAGTSLARLNLRKNYFLYLPVAGVLEHLNAIVQIDL
NENPWDCTCDLVPFKQWIETISSVSVVGDVLCRTPENLTHRDVRTIELEVLCPEMLHIAQPGPSPPQPGD
YHPNGGPTSASPYEFSPPGGPVPLSVLILSLLVLFFSAVFVAAGLFAYVLRRRRKKLPFRSKRQEGVDLT
GIQMQCHRLFEDSGGNSGGSGGGGRPTLSSPEKAPPVGHVYEYIPHPVTQMCNNPIYKPREEEEVAASAA
QDTGATDRGGPGTQPTGMAEVLLGSEQFAETPKENHSNYRTLLEKEKEWALAVSNSQLNTIVTVNHHHPH
PHHSAVGGVSGVGGGTGGDLAGFRHHEKNGGVVLFPPGGGCGGGSLLLDRERPQPAPCTVGFVDCLYGTV
PKLKELHVHPPGMQYPDLQQDARLKETLLFSAGKGFTDHQTPKSDYLDLRAKLQTKPDYLEVLEKTAYRF

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Chromatograms Chromatograms
Sequencher program is needed, download here
Restriction Sites SgfI-MluI Cloning Scheme for this gene | Plasmid Map
ACCN NM_198864
ORF Size 2940 bp
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution Method 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Shipping Ambient
Reference Data
RefSeq NM_198864.3
RefSeq Size 3751 bp
RefSeq ORF 2943 bp
Locus ID 386750
UniProt ID Q810B9
Cytogenetics 3 E3
MW 109.9 kDa
Summary Suppresses neurite outgrowth.UniProtKB/Swiss-Prot Function
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Documents
Resources
"NM_198864" in other vectors (4)
SKU Description Size Price
MC203461 Slitrk3 (untagged) - Mouse SLIT and NTRK-like family, member 3 (Slitrk3), (10ug) 10 ug
$898.00
MG211375 Slitrk3 (tGFP-tagged) - Mouse SLIT and NTRK-like family, member 3 (Slitrk3) 10 ug
$1,097.00
MR211375L3 Lenti ORF clone of Slitrk3 (Myc-DDK-tagged) - Mouse SLIT and NTRK-like family, member 3 (Slitrk3) 10 ug
$1,197.00
MR211375L4 Lenti ORF clone of Slitrk3 (mGFP-tagged) - Mouse SLIT and NTRK-like family, member 3 (Slitrk3) 10 ug
$1,197.00

Plasmid Map for MR211375

Download sequence for

file-download TXT (FASTA format)

file-download Genbank

Cloning scheme for MR211375
Circular map for MR211375

file-alt Citations

A critical role of Neuroligin 2 C-terminus in OCD and social behavior
Pandey, Ostergren, Li et al
J Neurosci (2025)
AI Summary: OriGene’s mouse full-length Slitrk3 cDNA (Cat #: MR211375) was used in this study to generate expression constructs for investigating the molecular mechanisms underlying Neuroligin 2’s role in OCD-like and social behaviors.
Snippet: The mouse full-length Slitrk3 cDNA was obtained from 185 OriGene (Cat #: MR211375) and cloned into the NheI and XhoI sites of the pCAGGS186 IRES-mCherry expression vector. The coding sequences for Neuroligin 2 and deletion 187 mutant NL2 StopKI were generated via overlapping PCR and subsequently inserted into 188 the pCAGGS-IRES-mCherry expression vector for neuronal expression
A Conserved Tyrosine Residue in Slitrk3 Carboxyl-Terminus Is Critical for GABAergic Synapse Development
Li, Han, Wu et al
Front Mol Neurosci (2019) 12, 213 DOI: 10.3389/fnmol.2019.00213
AI Summary: OriGene contributed to this study by providing the full-length mouse Slitrk3 (ST3) cDNA (Cat #: MR211375), which was used to investigate the role of ST3 and its mutants in GABAergic synapse development.
Snippet: under a 12-h light/dark cycle. Mice of either sex were used in this study. Plasmids. Full length mouse cDNA encoding Slitrk3 (ST3) in this study was purchased from OriGene (Cat #: MR211375). Flag- or Myc-tagged full length or
FigureFigureFigure
Molecular Dissection of Neuroligin 2 and Slitrk3 Reveals an Essential Framework for GABAergic Synapse Development
Li, Han, Pelkey et al
Neuron (2017) 96 (4), 808-826.e8 DOI: 10.1016/j.neuron.2017.10.003
Cited by 98
AI Summary: OriGene products contributed to this study by providing the Neuroligin 2 (NL2) and Slitrk3 (ST3) expression plasmids, which were essential for dissecting the molecular interactions underlying GABAergic synapse development.
FigureFigure
Molecular Dissection of Neuroligin 2 and Slitrk3 Reveals an Essential Framework for GABAergic Synapse Development
Li, Han, Pelkey et al
Neuron (2017) 96 (4), 808-826.e8 DOI: 10.1016/j.neuron.2017.10.003
AI Summary: OriGene’s mouse Slitrk3 cDNA plasmid (Cat#: MR211375) was used in this study to investigate the molecular interactions essential for GABAergic synapse development.
Snippet: In the brain, many types of interneurons make functionally diverse inhibitory synapses onto principal neurons. While numerous molecules have been identified to function Save;;Plasmid: mouse slitrk3 cDNA OriGene Cat#: MR211375 Plasmid: pFUSE-hIgG1-Fc2 InvivoGen Cat#: pfuse-hg1fc2, Version#: 06G05-MT
Showing 1-4 of 4 papers.
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