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Angptl4 (NM_020581) Mouse Tagged ORF Clone

  • TrueORF®
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SKU
MR206437
Angptl4 (Myc-DDK-tagged) - Mouse angiopoietin-like 4 (Angptl4)
Interest in protein/lysate? Submit request here!
ORF Plasmid:
DDK tGFP
Lentiviral Particles:
DDK w/ Puro mGFP w/ Puro
AAV Particle:
DDK
$289.00 $457.00
In Stock*
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Specifications
Specifications
Product Data
Type Mouse Tagged ORF Clone
Target Symbol Angptl4
Synonyms Arp4; Bk89; Fiaf; Hfarp; Ng27; Pgar; Pgarg; Pp1158
Vector pCMV6-Entry
E. coli Selection Kanamycin (25 ug/mL)
Mammalian Cell Selection Neomycin
Sequence Data
ORF Nucleotide Sequence
>MR206437 representing NM_020581
Red=Cloning site Blue=ORF Green=Tags(s)

TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
GCCGCGATCGCC

ATGCGCTGCGCTCCGACAGCAGGCGCTGCCCTGGTGCTATGCGCGGCTACTGCGGGGCTTTTGAGCGCGC
AAGGGCGCCCTGCACAGCCAGAGCCACCGCGCTTTGCATCCTGGGACGAGATGAACTTGCTGGCTCACGG
GCTGCTACAGCTCGGCCATGGGCTGCGCGAACACGTGGAGCGCACCCGTGGGCAGCTGGGCGCGCTGGAG
CGCCGCATGGCTGCCTGTGGTAACGCTTGTCAGGGGCCCAAGGGAAAAGATGCACCCTTCAAAGACTCCG
AGGATAGAGTCCCTGAAGGCCAGACTCCTGAGACTCTGCAGAGTTTGCAGACTCAGCTCAAGGCTCAAAA
CAGCAAGATCCAGCAATTGTTCCAGAAGGTGGCCCAGCAGCAGAGATACCTATCAAAGCAGAATCTGAGA
ATACAGAATCTTCAGAGCCAGATAGACCTCTTGGCCCCCACGCACCTAGACAATGGAGTAGACAAGACTT
CGAGGGGAAAGAGGCTTCCCAAGATGACCCAGCTCATTGGCTTGACTCCCAACGCCACCCACTTACACAG
GCCGCCCCGGGACTGCCAGGAACTCTTCCAAGAAGGGGAGAGGCACAGTGGACTTTTCCAGATCCAGCCT
CTGGGGTCTCCACCATTTTTGGTCAACTGTGAGATGACTTCAGATGGAGGCTGGACAGTGATTCAGAGAC
GCCTGAACGGCTCTGTGGACTTCAACCAGTCCTGGGAAGCCTACAAGGATGGCTTCGGAGATCCCCAAGG
CGAGTTCTGGCTGGGCCTGGAAAAGATGCACAGCATCACAGGGAACCGAGGAAGCCAATTGGCTGTGCAG
CTCCAGGACTGGGATGGCAATGCCAAATTGCTCCAATTTCCCATCCATTTGGGGGGTGAGGACACAGCCT
ACAGCCTGCAGCTCACTGAGCCCACGGCCAATGAGCTGGGTGCCACCAATGTTTCCCCCAATGGCCTTTC
CCTGCCCTTCTCTACTTGGGACCAAGACCATGACCTCCGTGGGGACCTTAACTGTGCCAAGAGCCTCTCT
GGTGGCTGGTGGTTTGGTACCTGTAGCCATTCCAATCTCAATGGACAATACTTCCACTCTATCCCACGGC
AACGGCAGGAGCGTAAAAAGGGTATCTTCTGGAAAACATGGAAGGGCCGCTACTATCCTCTGCAGGCTAC
CACCCTGCTGATCCAGCCCATGGAGGCTACAGCAGCCTCT

ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
ACAAGGATGACGACGATAAGGTTTAA
Protein Sequence
>MR206437 representing NM_020581
Red=Cloning site Green=Tags(s)

MRCAPTAGAALVLCAATAGLLSAQGRPAQPEPPRFASWDEMNLLAHGLLQLGHGLREHVERTRGQLGALE
RRMAACGNACQGPKGKDAPFKDSEDRVPEGQTPETLQSLQTQLKAQNSKIQQLFQKVAQQQRYLSKQNLR
IQNLQSQIDLLAPTHLDNGVDKTSRGKRLPKMTQLIGLTPNATHLHRPPRDCQELFQEGERHSGLFQIQP
LGSPPFLVNCEMTSDGGWTVIQRRLNGSVDFNQSWEAYKDGFGDPQGEFWLGLEKMHSITGNRGSQLAVQ
LQDWDGNAKLLQFPIHLGGEDTAYSLQLTEPTANELGATNVSPNGLSLPFSTWDQDHDLRGDLNCAKSLS
GGWWFGTCSHSNLNGQYFHSIPRQRQERKKGIFWKTWKGRYYPLQATTLLIQPMEATAAS

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Restriction Sites SgfI-MluI Cloning Scheme for this gene | Plasmid Map
ACCN NM_020581
ORF Size 1230 bp
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution Method 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Shipping Ambient
Reference Data
RefSeq NM_020581.1, NM_020581.2, NP_065606.1
RefSeq Size 1858 bp
RefSeq ORF 1233 bp
Locus ID 57875
UniProt ID Q9Z1P8
Cytogenetics 17 B1
MW 46 kDa
Summary Mediates inactivation of the lipoprotein lipase LPL, and thereby plays a role in the regulation of triglyceride clearance from the blood serum and in lipid metabolism (PubMed:15837923, PubMed:17609370, PubMed:29899519). May also play a role in regulating glucose homeostasis and insulin sensitivity (PubMed:15837923, PubMed:29899519). Inhibits proliferation, migration, and tubule formation of endothelial cells and reduces vascular leakage (PubMed:14583458, PubMed:17130448, PubMed:21832056). Upon heterologous expression, inhibits the adhesion of endothelial cell to the extracellular matrix (ECM), and inhibits the reorganization of the actin cytoskeleton, formation of actin stress fibers and focal adhesions in endothelial cells that have adhered to ANGPTL4-containing ECM (in vitro) (By similarity). Depending on context, may modulate tumor-related angiogenesis (Probable).UniProtKB/Swiss-Prot Function
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Documents
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"NM_020581" in other vectors (4)
SKU Description Size Price
MC200784 Angptl4 (untagged) - Mouse angiopoietin-like 4 (Angptl4), (10ug) 10 ug
$457.00
MG206437 Angptl4 (tGFP-tagged) - Mouse angiopoietin-like 4 (Angptl4) 10 ug
$657.00
MR206437L3 Lenti ORF clone of Angptl4 (Myc-DDK-tagged) - Mouse angiopoietin-like 4 (Angptl4) 10 ug
$757.00
MR206437L4 Lenti ORF clone of Angptl4 (mGFP-tagged) - Mouse angiopoietin-like 4 (Angptl4) 10 ug
$757.00

Plasmid Map for MR206437

Download sequence for

file-download TXT (FASTA format)

file-download Genbank

Cloning scheme for MR206437
Circular map for MR206437

file-alt Citations

ANGPTL3 orchestrates hepatic fructose sensing and metabolism
Zhao, Linde-Garelli, Zhang et al
Cell Rep (2025) 44 (7), 115962 DOI: 10.1016/j.celrep.2025.115962
Cited by 8
AI Summary: OriGene products contributed to this study by providing Angptl3 (MR207262), Angptl4 (MR206437), and Tsk (MR218507) expression plasmids, which were used to investigate the roles of these genes in hepatic fructose metabolism.
Snippet: Angptl3 expression plasmid OriGene MR207262 Angptl4 expression plasmid OriGene MR206437 Tsk expression plasmid OriGene MR218507
Showing 1-1 of 1 papers.
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