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Itgb3bp (NM_026348) Mouse Tagged ORF Clone

  • TrueORF®
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SKU
MR201548
Itgb3bp (Myc-DDK-tagged) - Mouse integrin beta 3 binding protein (beta3-endonexin) (Itgb3bp)
Interest in protein/lysate? Submit request here!
ORF Plasmid:
DDK tGFP
Lentiviral Particles:
DDK w/ Puro mGFP w/ Puro
AAV Particle:
DDK
$289.00 $300.00
In Stock*
Bulk Requests & Clone Modifications

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Other products for "Itgb3bp or NM_026348"

Specifications
Specifications
Product Data
Type Mouse Tagged ORF Clone
Target Symbol Itgb3bp
Synonyms 4930471O16Rik; AU022583
Vector pCMV6-Entry
E. coli Selection Kanamycin (25 ug/mL)
Mammalian Cell Selection Neomycin
Sequence Data
ORF Nucleotide Sequence
>MR201548 representing NM_026348
Red=Cloning site Blue=ORF Green=Tags(s)

TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
GCCGCGATCGCC

ATGCCAGTTAAAAGATCACTGAAACTGGATGATCAGTTTGAAAAAAATTCATTTAGTCCTTCAAAAATCG
TGAGGAAGAAAAGTATTACAGCTTATTCTCCTACTACTGGAACTTATCAGTTGAGCCCATTTTCTTCTCC
CGCAACCCCCAAAGAACAGGAGCACAGAAACGGACCATCAAATGAAACAAGGAAACGGAGTAACTTGAGC
TCACCTGTAAGACAGGAGTCCACAGTGAAAGACAGGGATGGATTCATGGTGTTGCTATCTAAAATTGAGA
TATCATCAGAGAAAACCATGGAGATAATGAAAAATCTAAGTAGTATACAGGCTTTGGAGGGCAACAGACA
ACTTGAAGATCTCATTGGTGTTTCCCTAGTACCATGCTCCTTAAAAAGTGAAGCAAGGAAAACCAAAGAA
CTAATGACTAAAGTAATAAAACAAAAGTTGTTTGAAAAGAAAAAATCAAGAATTACTCCCAAAGATCATC
ATCTTGACAGCTTTGAATTCCTTAAAGCCATTTTGAAC

ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
ACAAGGATGACGACGATAAGGTTTAA
Chromatograms Chromatograms
Sequencher program is needed, download here
Restriction Sites SgfI-MluI Cloning Scheme for this gene | Plasmid Map
ACCN NM_026348
ORF Size 528 bp
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution Method 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Shipping Ambient
Reference Data
RefSeq NM_026348.4
RefSeq Size 2738 bp
RefSeq ORF 531 bp
Locus ID 67733
UniProt ID Q9CQ82
Cytogenetics 4 C6
MW 20.5 kDa
Summary Transcription coregulator that can have both coactivator and corepressor functions. Involved in the coactivation of nuclear receptors for retinoid X (RXRs) and thyroid hormone (TRs) in a ligand-dependent fashion. In contrast, it does not coactivate nuclear receptors for retinoic acid, vitamin D, progesterone receptor, nor glucocorticoid. Acts as a coactivator for estrogen receptor alpha. Acts as a transcriptional corepressor via its interaction with the NFKB1 NF-kappa-B subunit, possibly by interfering with the transactivation domain of NFKB1. Induces apoptosis in breast cancer cells, but not in other cancer cells, via a caspase-2 mediated pathway that involves mitochondrial membrane permeabilization but does not require other caspases. May also act as an inhibitor of cyclin A-associated kinase. Also acts a component of the CENPA-CAD (nucleosome distal) complex, a complex recruited to centromeres which is involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation. May be involved in incorporation of newly synthesized CENPA into centromeres via its interaction with the CENPA-NAC complex (By similarity).UniProtKB/Swiss-Prot Function
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"NM_026348" in other vectors (4)
SKU Description Size Price
MC205135 Itgb3bp (untagged) - Mouse integrin beta 3 binding protein (beta3-endonexin) (Itgb3bp), (10ug) 10 ug
$300.00
MG201548 Itgb3bp (tGFP-tagged) - Mouse integrin beta 3 binding protein (beta3-endonexin) (Itgb3bp) 10 ug
$500.00
MR201548L3 Lenti ORF clone of Itgb3bp (Myc-DDK-tagged) - Mouse integrin beta 3 binding protein (beta3-endonexin) (Itgb3bp) 10 ug
$600.00
MR201548L4 Lenti ORF clone of Itgb3bp (mGFP-tagged) - Mouse integrin beta 3 binding protein (beta3-endonexin) (Itgb3bp) 10 ug
$600.00

Plasmid Map for MR201548

Download sequence for

file-download TXT (FASTA format)

file-download Genbank

Cloning scheme for MR201548
Circular map for MR201548

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