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Itgb3bp (NM_026348) Mouse Untagged Clone

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SKU
MC205135
Itgb3bp (untagged) - Mouse integrin beta 3 binding protein (beta3-endonexin) (Itgb3bp), (10ug)
Interest in protein/lysate? Submit request here!
ORF Plasmid:
Tag Free tGFP DDK
AAV Particle:
DDK
  $300.00
In Stock*
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Specifications
Specifications
Product Data
Type Mouse Untagged Clone
Target Symbol Itgb3bp
Synonyms 4930471O16Rik; AU022583
Vector PCMV6-Kan/Neo
E. coli Selection Kanamycin (25 ug/mL)
Mammalian Cell Selection Neomycin
Sequence Data
Fully Sequenced ORF
>BC049557
GCGGTTTCTCAGTTGGTTCTGTCCAGCAACGGAGTCCCGAAATGCCAGTTAAAAGATCACTGAAACTGGA TGATCAGTTTGAAAAAAATTCATTTAGTCCTTCAAAAATCGTGAGGAAGAAAAGTATTACAGCTTATTCT CCTACTACTGGAACTTATCAGTTGAGCCCATTTTCTTCTCCCGCAACCCCCAAAGAACAGGAGCACAGAA ACGGACCATCAAATGAAACAAGGAAACGGAGTAACTTGAGCTCACCTGTAAGACAGGAGTCCACAGTGAA AGACAGGGATGGATTCATGGTGTTGCTATCTAAAATTGAGATATCATCAGAGAAAACCATGGAGATAATG AAAAATCTAAGTAGTATACAGGCTTTGGAGGGCAACAGACAACTTGAAGATCTCATTGGTGTTTCCCTAG TACCATGCTCCTTAAAAAGTGAAGCAAGGAAAACCAAAGAACTAATGACTAAAGTAATAAAACAAAAGTT GTTTGAAAAGAAAAAATCAAGAATTACTCCCAAAGATCATCATCTTGACAGCTTTGAATTCCTTAAAGCC ATTTTGAACTGAGTGTTACCTTCAAGTCTGACAACTGTCAACCTACCTGGATACTAGTCAAGCCGTAAGA ATGCAGACCAGCCTGAAGTAAAGAGTCAGTGAAAGACTGTCACATTTGCAACCTTTCTTAAAAGACGATA TGCTGAGTATTCTAAATAGGAAAAAAATAAAGGCATCCACCGTGAAAAAAAAAAAAAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAATAAAAAAAAAAAAAAAA AAAAAAAAAAAAAA
Restriction Sites SfiI-SfiI |
ACCN NM_026348
Insert Size 531 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution Method 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Shipping Ambient
Reference Data
RefSeq BC049557, AAH49557
RefSeq Size 854 bp
RefSeq ORF 531 bp
Locus ID 67733
UniProt ID Q9CQ82
Cytogenetics 4 C6
Summary Transcription coregulator that can have both coactivator and corepressor functions. Involved in the coactivation of nuclear receptors for retinoid X (RXRs) and thyroid hormone (TRs) in a ligand-dependent fashion. In contrast, it does not coactivate nuclear receptors for retinoic acid, vitamin D, progesterone receptor, nor glucocorticoid. Acts as a coactivator for estrogen receptor alpha. Acts as a transcriptional corepressor via its interaction with the NFKB1 NF-kappa-B subunit, possibly by interfering with the transactivation domain of NFKB1. Induces apoptosis in breast cancer cells, but not in other cancer cells, via a caspase-2 mediated pathway that involves mitochondrial membrane permeabilization but does not require other caspases. May also act as an inhibitor of cyclin A-associated kinase. Also acts a component of the CENPA-CAD (nucleosome distal) complex, a complex recruited to centromeres which is involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation. May be involved in incorporation of newly synthesized CENPA into centromeres via its interaction with the CENPA-NAC complex (By similarity).UniProtKB/Swiss-Prot Function
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"NM_026348" in other vectors (4)
SKU Description Size Price
MG201548 Itgb3bp (tGFP-tagged) - Mouse integrin beta 3 binding protein (beta3-endonexin) (Itgb3bp) 10 ug
$500.00
MR201548 Itgb3bp (Myc-DDK-tagged) - Mouse integrin beta 3 binding protein (beta3-endonexin) (Itgb3bp) 10 ug
$289.00 $300.00
MR201548L3 Lenti ORF clone of Itgb3bp (Myc-DDK-tagged) - Mouse integrin beta 3 binding protein (beta3-endonexin) (Itgb3bp) 10 ug
$600.00
MR201548L4 Lenti ORF clone of Itgb3bp (mGFP-tagged) - Mouse integrin beta 3 binding protein (beta3-endonexin) (Itgb3bp) 10 ug
$600.00

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