Drc1 (NM_001033460) Mouse Untagged Clone

SKU MC221349

Drc1 (untagged) - Mouse coiled-coil domain containing 164 (Ccdc164), (10ug)

Product Data

• Type: Mouse Untagged Clone
• Target Symbol: Drc1
• Synonyms: b2b1654Clo; Ccdc164; Gm1060
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >MC221349 representing NM_001033460; Red=Cloning site Blue=ORF Orange=Stop codon; ; TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC; GCCGCGATCGCC; ; ATGAATCCCTCAGGAACCATTGGGGTCCTAGAGCAGAATGGGGAAGAACACTTAGCCACCCCGATTCTCG; GACCCTCGGTGCATTCGGATAACCCGCAGGAGCGGATCCAGGCCCGGCGCCTGCGCATCGCTGCTCGTCA; GGAAGCCCGAAGGCGGGAAGCCCTGGGAGAGTATTTGGACGGGAAGAAGGAGAGTGAGGAGGAGCAGAGC; AAGAGCTACAAACAGAAAGAAGAGAGCCGCCTGAAACTGACTAAACTCCTGCTCTGCGGGACCGAGTTGG; TGACAAATATTCAGGTGGCTGCAGACGTCAGAGAGATCCACAGGAGGGTTGAAGAGGAGGAGACAAAGCG; GCAGAGACTGGAGAAGCTGGAGAATGAAGTTAAGACCAGCCAGGATAAATTTGATGAAATCACGGCGAAG; TGGGAGGAGGGCAGACGGAAGCGGATTCCCCAGGAACTGTGGGAGATGCTCAACAGCCAGCAGGTGCACT; GTGCTGAGCTCATAGAAGACAAGAACAAGCTGGCCAACGAGCTGCAGCAGGAGTTAAAAATAAAGGATGA; CCAGTATGTGAAGGACTTGAAGAAACAGTCGGAAGACATCACCCTGATTCTGGAGAGAATGGAGGAGCAG; GTGAAGAATGTGATGAAGAACTTCCGCCAGGAGCTGATTCACATCGAGAAAGCCTTTGAGTCAGAACGGC; AAGAACTGCTATCCAGCAATAAGAAGAAATGGGAGCGAGCCCTGCAGGCTCACAATGCCAAGGAGCTGGA; GTACCTCACCAACCGCATGAAGAAGGTGGAGGACTACGAGAAGCAGCTCAACAAGCAGCGGGTCTGGGAC; TGTGAGGAGTACAACACAATCAAGATCAAGCTAGAGCAGGATGTGCAGATTCTTGAGCAACAGCTTCAGC; AGATGAAAGCAACTTACCAGCTAAACCAAGAGAAGCTGGAGTACAACTTTCAGGTCCTGAAGAAGAGAGA; TGAAGAGAGCACAGTGATCAAGTCCCAGCAGAAGAGGAAACTGAACCGCCTGCACGATGTCGTCAACAAT; CTGAGAACAAAATACACCAAGCAGATACGGCAGTTTCAGGATGACAACCAGTCCCTGACCTCCGACTACA; AACGGCTTGTGACGCAATTCAAGGACCTACAGAAAGCCTTGAGACACTTCATCATCATCGATGAGGAGAA; GTTTCGGGAGATTTGGCTGATGAATGAAGCAGAGGCGAAGGAACTGGCACAAAGAGCCTTTGATGTGGAC; AGGATCATCCATTCCCAGCACCTGGGCTTACCCTGGAATATGCCTGACTTGTGGTTCCTGAATAACGTGG; GGCCGATTTCCCTGCAGCAGCAGAAGTCAGTCACACAAATACTGGAGGAACTGCTGTTGCAGACAGAGGA; TGAGGCCACAGAGGCAGCCATGTCGGAAGACGAGGATTACATGGACCTGCCCAATCAAATTTCAGCCAAA; ACCACCACAAAGGTCCTGATGCTCCTGTGTGATGAGTCGGGTTTCCTCATAGAGAGCAAACTACTGAGTC; TGCTCCACCCCCTGGAGAAGAGTGAATGCTATCTGCTGAGGTTGGACGCCATCTTCTCCGCCCTGGCAAT; CGAAGACGAGGATGACTTATACAAGCTGGTAAACTTCTTCCTTCGATACCGAGCCCACCGTCTATCCTCT; GCCCAGGCCAGTTCCTCCATTCATAGCAATGTGGAGCGTACAAGCCTGATGTCAGCACTAGAGCGTTTGA; GTCTGATGTCCCAGACAGACAAGGGAAGCATGGTGTCCAAATCAGATCAGGAGCCCACAGAGCAGGAGGA; CGAGCAGGAAGGTGACAACGCAAGCCTCTCGAGCAGGGAGTTGGAAGAGCAGGAGGACCTGTCATCACCC; AGGTTCATCCACCCCAATGATGTTCTCAAGATTCTGGAGGCCTTTGTCACGGGGCTGAAGAAGCCTAAGG; ACGCTCAGCCAGTACTGAAATTGAAGAAAGAGACTCGAGATAACTCGAAGGACACGGAGTACTGGGAATC; CCTGGCTGCGGTTATTCCTTTCTTCAAGCAGAACCTCTGGGATGCGCTGTACAAGGCCTTGGAGAAATAC; TATCTCGTGCTGACCGAGAGGGCCAAGCTGCTGATGGAGAATGAGTCTCTGGAGCAGCAGAATGCAGAGA; TGCAGTCCCTGCTGCAGCAGTATCTCCAGGCCAAGGTAAACACAGAACTGCAGATCCCACCAACTCAGGG; CTTCCGGATGCCCTCAAAATGA; ; ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT; ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: NM_001033460
• Insert Size: 2262 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution Method: 1. Centrifuge at 5,000xg for 5min.; 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.; 3. Close the tube and incubate for 10 minutes at room temperature.; 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.; 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
• Note: Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001033460.3, NP_001028632.1
• RefSeq Size: 2485 bp
• RefSeq ORF: 2262 bp
• Locus ID: 381738
• UniProt ID: Q3USS3
• Cytogenetics: 5 B1
• Summary: Component of the nexin-dynein regulatory complex (N-DRC) a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes. Plays a critical role in the assembly of N-DRC and also stabilizes the assembly of multiple inner dynein arms and radial spokes. Coassembles with CCDC65/DRC2 to form a central scaffold needed for assembly of the N-DRC and its attachment to the outer doublet microtubules.[UniProtKB/Swiss-Prot Function]