Dnajc2 (NM_009584) Mouse Untagged Clone
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
|---|---|
| Target Symbol | Dnajc2 |
| Synonyms | AU020218; MIDA1; Zrf1; Zrf2 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data | |
| Restriction Sites | SgfI-MluI | |
| ACCN | NM_009584 |
| Insert Size | 1866 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution Method | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | BC052027, AAH52027 |
| RefSeq Size | 2086 bp |
| RefSeq ORF | 1866 bp |
| Locus ID | 22791 |
| UniProt ID | P54103 |
| Cytogenetics | 5 9.97 cM |
| Summary | Acts both as a chaperone in the cytosol and as a chromatin regulator in the nucleus. When cytosolic, acts as a molecular chaperone: component of the ribosome-associated complex (RAC), a complex involved in folding or maintaining nascent polypeptides in a folding-competent state. In the RAC complex, stimulates the ATPase activity of the ribosome-associated pool of Hsp70-type chaperones HSPA14 that bind to the nascent polypeptide chain. When nuclear, mediates the switching from polycomb-repressed genes to an active state: specifically recruited at histone H2A ubiquitinated at 'Lys-119' (H2AK119ub), and promotes the displacement of the polycomb PRC1 complex from chromatin, thereby facilitating transcription activation (By similarity). Specifically binds DNA sequence 5'-GTCAAGC-3'.UniProtKB/Swiss-Prot Function |
Reviews
Documents
| Product Manuals |
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Resources
"NM_009584" in other vectors (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| MG209498 | Dnajc2 (tGFP-tagged) - Mouse DnaJ (Hsp40) homolog, subfamily C, member 2 (Dnajc2) | 10 ug |
$779.00
|
|
| MR209498 | Dnajc2 (Myc-DDK-tagged) - Mouse DnaJ (Hsp40) homolog, subfamily C, member 2 (Dnajc2) | 10 ug |
$289.00
$579.00
|
|
| MR209498L3 | Lenti ORF clone of Dnajc2 (Myc-DDK-tagged) - Mouse DnaJ (Hsp40) homolog, subfamily C, member 2 (Dnajc2) | 10 ug |
$879.00
|
|
| MR209498L4 | Lenti ORF clone of Dnajc2 (mGFP-tagged) - Mouse DnaJ (Hsp40) homolog, subfamily C, member 2 (Dnajc2) | 10 ug |
$879.00
|
|
Citations
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