Parp2 (NM_009632) Mouse Untagged Clone
$573.00
3 Weeks*
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
|---|---|
| Target Symbol | Parp2 |
| Synonyms | Adprt2; Adprtl2; ARTD2; Aspartl2; C78626; PARP-2 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data | |
| Restriction Sites | SgfI-MluI | |
| ACCN | NM_009632 |
| Insert Size | 1680 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution Method | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | NM_009632.2, NP_033762.1 |
| RefSeq Size | 1834 bp |
| RefSeq ORF | 1680 bp |
| Locus ID | 11546 |
| UniProt ID | O88554 |
| Cytogenetics | 14 C1 |
| Summary | Poly-ADP-ribosyltransferase that mediates poly-ADP-ribosylation of proteins and plays a key role in DNA repair (PubMed:10364231). Mainly mediates glutamate and aspartate ADP-ribosylation of target proteins: the ADP-D-ribosyl group of NAD(+) is transferred to the acceptor carboxyl group of glutamate and aspartate residues and further ADP-ribosyl groups are transferred to the 2'-position of the terminal adenosine moiety, building up a polymer with an average chain length of 20-30 units (By similarity). ADP-ribosylation follows DNA damage and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks (PubMed:10364231). Also mediates serine ADP-ribosylation of target proteins following interaction with HPF1; HPF1 conferring serine specificity (By similarity). In addition to proteins, also able to ADP-ribosylate DNA: preferentially acts on 5'-terminal phosphates at DNA strand breaks termini in nicked duplex (By similarity).UniProtKB/Swiss-Prot Function |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
"NM_009632" in other vectors (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| MG208862 | Parp2 (tGFP-tagged) - Mouse poly (ADP-ribose) polymerase family, member 2 (Parp2) | 10 ug |
$720.00
|
|
| MR208862 | Parp2 (Myc-DDK-tagged) - Mouse poly (ADP-ribose) polymerase family, member 2 (Parp2) | 10 ug |
$289.00
$520.00
|
|
| MR208862L3 | Lenti ORF clone of Parp2 (Myc-DDK-tagged) - Mouse poly (ADP-ribose) polymerase family, member 2 (Parp2) | 10 ug |
$820.00
|
|
| MR208862L4 | Lenti ORF clone of Parp2 (mGFP-tagged) - Mouse poly (ADP-ribose) polymerase family, member 2 (Parp2) | 10 ug |
$820.00
|
|
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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