Dmap1 (NM_023178) Mouse Untagged Clone
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
|---|---|
| Target Symbol | Dmap1 |
| Synonyms | 1500016M21Rik; Dmtap1; DNMAP1; DNMTAP1; mKIAA1425 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data | |
| Restriction Sites | SgfI-MluI | |
| ACCN | NM_023178 |
| Insert Size | 1407 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution Method | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | NM_023178.2, NP_075667.1 |
| RefSeq Size | 1543 bp |
| RefSeq ORF | 1407 bp |
| Locus ID | 66233 |
| UniProt ID | Q9JI44 |
| Cytogenetics | 4 D2.1 |
| Summary | Involved in transcription repression and activation. Its interaction with HDAC2 may provide a mechanism for histone deacetylation in heterochromatin following replication of DNA at late firing origins. Can also repress transcription independently of histone deacetylase activity. May specifically potentiate DAXX-mediated repression of glucocorticoid receptor-dependent transcription. Component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when recruited to sites of DNA damage. Participates in the nuclear localization of URI1 and increases its transcriptional corepressor activity (By similarity).UniProtKB/Swiss-Prot Function |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
"NM_023178" in other vectors (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| MG207480 | Dmap1 (tGFP-tagged) - Mouse DNA methyltransferase 1-associated protein 1 (Dmap1) | 10 ug |
$657.00
|
|
| MR207480 | Dmap1 (Myc-DDK-tagged) - Mouse DNA methyltransferase 1-associated protein 1 (Dmap1) | 10 ug |
$289.00
$457.00
|
|
| MR207480L3 | Lenti ORF clone of Dmap1 (Myc-DDK-tagged) - Mouse DNA methyltransferase 1-associated protein 1 (Dmap1) | 10 ug |
$757.00
|
|
| MR207480L4 | Lenti ORF clone of Dmap1 (mGFP-tagged) - Mouse DNA methyltransferase 1-associated protein 1 (Dmap1) | 10 ug |
$757.00
|
|
Citations
Related Products
- Price:
- Actual Price:
Welcome to OriGene AI!
I'm your AI-powered guide to everything OriGene.
Ask me anything:
- Product specs
- Ordering help
- Technical questions
- How to find exactly what your experiment needs
Prefer a live agent? Connect with us by clicking the green chat icon, as seen in the image below or email our team at custsupport@origene.com.