Lamtor2 (NM_031248) Mouse Untagged Clone

SKU
MC211959
Lamtor2 (untagged) - Mouse late endosomal/lysosomal adaptor, MAPK and MTOR activator 2 (Lamtor2), (10ug)
  $165.00
2 Weeks*
Specifications
Specifications
Product Data
Type Mouse Untagged Clone
Target Symbol Lamtor2
Synonyms 2010111E04Rik; AL022628; Mapbpip; P14; Rab25; Robld3
Vector pCMV6-Entry
E. coli Selection Kanamycin (25 ug/mL)
Mammalian Cell Selection Neomycin
Sequence Data
Fully Sequenced ORF
>MC211959 representing NM_031248
Red=Cloning site Blue=ORF Orange=Stop codon

TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
GCCGCGATCGCC

ATGCTGCGTCCCAAGGCTTTGACGCAGGTGCTAAGCCAAGCCAACACTGGAGGAGTCCAGAGCACCCTGC
TGCTGAATAATGAGGGATCGCTGCTGGCCTACTCCGGTTATGGGGACACAGATGCCCGGGTCACTGCGGC
CATCGCCAGTAACATCTGGGCCGCGTATGATAGGAACGGGAACCAAGCGTTTAATGAAGACAGTCTCAAA
TTTATCCTGATGGACTGCATGGAGGGCCGTGTAGCCATTACGAGGGTGGCCAACCTTCTGCTATGTATGT
ATGCCAAGGAGACCGTAGGCTTCGGAATGCTCAAGGCTAAGGCCCAGGCCCTGGTGCAGTACCTGGAGGA
ACCCCTCACCCAAGTAGCAGCATCATAA


ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
ACAAGGATGACGACGATAAGGTTTAA
Restriction Sites SgfI-MluI |
ACCN NM_031248
Insert Size 378 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution Method 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Shipping Ambient
Reference Data
RefSeq NM_031248.3, NP_112538.1
RefSeq Size 586 bp
RefSeq ORF 378 bp
Locus ID 83409
UniProt ID Q9JHS3
Cytogenetics 3 F1
Summary As part of the Ragulator complex it is involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Activated by amino acids through a mechanism involving the lysosomal V-ATPase, the Ragulator functions as a guanine nucleotide exchange factor activating the small GTPases Rag. Activated Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated. Adapter protein that enhances the efficiency of the MAP kinase cascade facilitating the activation of MAPK2.UniProtKB/Swiss-Prot Function
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Resources
"NM_031248" in other vectors (4)
SKU Description Size Price
MG200653 Lamtor2 (tGFP-tagged) - Mouse mitogen activated protein binding protein interacting protein (Mapbpip) 10 ug
$350.00
MR200653 Lamtor2 (Myc-DDK-tagged) - Mouse late endosomal/lysosomal adaptor, MAPK and MTOR activator 2 (Lamtor2) 10 ug
$289.00
MR200653L3 Lenti ORF clone of Lamtor2 (Myc-DDK-tagged) - Mouse late endosomal/lysosomal adaptor, MAPK and MTOR activator 2 (Lamtor2) 10 ug
$450.00
MR200653L4 Lenti ORF clone of Lamtor2 (mGFP-tagged) - Mouse late endosomal/lysosomal adaptor, MAPK and MTOR activator 2 (Lamtor2) 10 ug
$450.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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