Pim3 (NM_145478) Mouse Untagged Clone
$300.00
In Stock*
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
|---|---|
| Target Symbol | Pim3 |
| Synonyms | BC026639; Kid1 |
| Vector | PCMV6-Kan/Neo |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data | |
| Restriction Sites | RsrII-NotI | |
| ACCN | NM_145478 |
| Insert Size | 981 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution Method | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | BC017621, AAH17621 |
| RefSeq Size | 2447 bp |
| RefSeq ORF | 981 bp |
| Locus ID | 223775 |
| UniProt ID | P58750 |
| Cytogenetics | 15 E3 |
| Summary | Proto-oncogene with serine/threonine kinase activity that can prevent apoptosis and promote cell survival and protein translation. May contribute to tumorigenesis through: the delivery of survival signaling through phosphorylation of BAD which induces release of the anti-apoptotic protein Bcl-X(L), the regulation of cell cycle progression and protein synthesis and by regulation of MYC transcriptional activity. Additionally to this role on tumorigenesis, can also negatively regulate insulin secretion by inhibiting the activation of MAPK1/3 (ERK1/2), through SOCS6. Involved also in the control of energy metabolism and regulation of AMPK activity in modulating MYC and PPARGC1A protein levels and cell growth.UniProtKB/Swiss-Prot Function |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
"NM_145478" in other vectors (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| MG204756 | Pim3 (tGFP-tagged) - Mouse proviral integration site 3 (Pim3) | 10 ug |
$500.00
|
|
| MR204756 | Pim3 (Myc-DDK-tagged) - Mouse proviral integration site 3 (Pim3) | 10 ug |
$289.00
$300.00
|
|
| MR204756L3 | Lenti ORF clone of Pim3 (Myc-DDK-tagged) - Mouse proviral integration site 3 (Pim3) | 10 ug |
$600.00
|
|
| MR204756L4 | Lenti ORF clone of Pim3 (mGFP-tagged) - Mouse proviral integration site 3 (Pim3) | 10 ug |
$600.00
|
|
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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