Ubiad1 (NM_027873) Mouse Untagged Clone
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
|---|---|
| Target Symbol | Ubiad1 |
| Synonyms | 1200002M06Rik; AI426463; AW320947; Tere1 |
| Vector | PCMV6-Kan/Neo |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data | |
| Restriction Sites | RsrII-NotI | |
| ACCN | NM_027873 |
| Insert Size | 1011 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution Method | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | BC071203, AAH71203 |
| RefSeq Size | 2976 bp |
| RefSeq ORF | 1011 bp |
| Locus ID | 71707 |
| UniProt ID | Q9DC60 |
| Cytogenetics | 4 E2 |
| Summary | Prenyltransferase that mediates the formation of menaquinone-4 (MK-4) and coenzyme Q10. MK-4 is a vitamin K2 isoform required for endothelial cell development. Mediates the conversion of phylloquinone (PK) into MK-4, probably by cleaving the side chain of phylloquinone (PK) to release 2-methyl-1,4-naphthoquinone (menadione; K3) and then prenylating it with geranylgeranyl pyrophosphate (GGPP) to form MK-4. Also plays a role in cardiovascular development independently of MK-4 biosynthesis, by acting as a coenzyme Q10 biosynthetic enzyme: coenzyme Q10, also named ubiquinone, plays an important antioxidant role in the cardiovascular system. Mediates biosynthesis of coenzyme Q10 in the Golgi membrane, leading to protect cardiovascular tissues from NOS3/eNOS-dependent oxidative stress (By similarity).UniProtKB/Swiss-Prot Function |
Reviews
Documents
| Product Manuals |
| FAQs |
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Resources
"NM_027873" in other vectors (3)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| MR204986 | Ubiad1 (Myc-DDK-tagged) - Mouse UbiA prenyltransferase domain containing 1 (Ubiad1) | 10 ug |
$289.00
$457.00
|
|
| MR204986L3 | Lenti ORF clone of Ubiad1 (Myc-DDK-tagged) - Mouse UbiA prenyltransferase domain containing 1 (Ubiad1) | 10 ug |
$757.00
|
|
| MR204986L4 | Lenti ORF clone of Ubiad1 (mGFP-tagged) - Mouse UbiA prenyltransferase domain containing 1 (Ubiad1) | 10 ug |
$757.00
|
|
Citations
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