Cirbp (NM_007705) Mouse Untagged Clone

SKU
MC203526
Cirbp (untagged) - Mouse cold inducible RNA binding protein (Cirbp), (10ug)
  $300.00
In Stock*
Specifications
Specifications
Product Data
Type Mouse Untagged Clone
Target Symbol Cirbp
Synonyms Cirp; R74941
Vector PCMV6-Kan/Neo
E. coli Selection Kanamycin (25 ug/mL)
Mammalian Cell Selection Neomycin
Sequence Data
Fully Sequenced ORF
>BC075699
TAGGAAGCTTGGGTGTGTGTGGCGCGCTGTCTTCCCGCTCGCGTCAGGGACCTGCCCGACTCAGCGGCTG CCATGGCATCAGATGAAGGCAAGCTTTTCGTGGGAGGACTCAGCTTCGACACCAACGAGCAGGCGCTGGA GCAGGTCTTCTCCAAGTATGGGCAGATCTCCGAAGTGGTGGTGGTAAAGGACAGGGAGACCCAGCGATCC CGAGGCTTTGGGTTTGTCACCTTTGAAAATATCGATGACGCTAAGGACGCCATGATGGCTATGAATGGGA AGTCTGTGGACGGGCGGCAGATCAGAGTTGACCAGGCTGGCAAGTCTTCTGACAACCGGTCCCGAGGATA CCGGGGTGGCTCTGCTGGAGGCCGGGGCTTTTTCCGTGGGGGACGAAGCCGGGGCCGAGGGTTCTCCAGA GGAGGAGGAGACCGGGGCTATGGAGGTGGCCGCTTTGAGTCCCGGAGTGGGGGTTATGGAGGCTCCAGAG ACTACTATGCCAGCCGGAGTCAGGGTGGCAGCTATGGTTATCGGAGCTCGGGAGGGTCCTACAGAGACAG CTATGACAGTTATGCTACACACAACGAGTAAAAGCCCTCCGCGTCCAGATCGTCCTTCCATGGCTGTAAT TAAGATGGGGGAGCTTCGCTGATCGTTGTGTAGTGAGCACCTTGTTCCCACTTTTGTAGTCCTTTCCGTT CTGACCCGTCAGCAGCCTGCTTCTGACCCAAGATGGCCTCGTGACTAGACCTGTTTTTAAGGAAGCGCTG TCTGTTTTTAAGTATTCTTAAAAACGTTTTGGAAAGCACTTCAGATTTTACTGTTTACCATGAGCCATGG GTTTTTGTTTTTTCTAAATTGTCGGGTTGTGTGGGTTTTGGTTACTCGTTTTTGTTTTTTCAGGTTTTTT GGTTGTGGCTTTTCTTTTTTTTTCTTTTTTTGTGTGGTCGCCCCTGAAGTCTGGCGCCCCACCCCTCCTG AGATGGAATGGACTCGATTTGAGCAAGCCATGGCCCTCCAGCTCCCCAGCCCGGCTGCGGAGTTGCAGCA GGTCCTGCCCATCGGGCACATGTCTCAAGCCCATGGGGAGCATAGCAGTCCGGGAGGCTGTGGAAATGTT TATTTATATTGTCCTTTTTTACCGAAGACATGCATACTCCATCGATGTTGTATTCACAGTGGCTGAGGAA TTCTTGTACGCAGTTTCTTTGGCTTCACGAAGCCGATTAAAAGACCGTGTGAAATGAAAAAAAAAAAAAA AAAAAAAAAAAAAAAA
Restriction Sites AscI-NotI |
ACCN NM_007705
Insert Size 519 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution Method 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Shipping Ambient
Reference Data
RefSeq BC075699, AAH75699
RefSeq Size 1276 bp
RefSeq ORF 519 bp
Locus ID 12696
UniProt ID P60824
Cytogenetics 10 39.72 cM
Summary Cold-inducible mRNA binding protein that plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. Promotes assembly of stress granules (SGs), when overexpressed. Seems to play an essential role in cold-induced suppression of cell proliferation. Acts as a translational repressor. Acts as a translational activator. Binds specifically to the 3'-untranslated regions (3' UTRs) of stress-responsive transcripts RPA2 and TXN.UniProtKB/Swiss-Prot Function
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Documents
Resources
"NM_007705" in other vectors (4)
SKU Description Size Price
MG201471 Cirbp (tGFP-tagged) - Mouse cold inducible RNA binding protein (Cirbp) 10 ug
$500.00
MR201471 Cirbp (Myc-DDK-tagged) - Mouse cold inducible RNA binding protein (Cirbp) 10 ug
$289.00 $300.00
MR201471L3 Lenti ORF clone of Cirbp (Myc-DDK-tagged) - Mouse cold inducible RNA binding protein (Cirbp) 10 ug
$600.00
MR201471L4 Lenti ORF clone of Cirbp (mGFP-tagged) - Mouse cold inducible RNA binding protein (Cirbp) 10 ug
$600.00

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