Bin1 (NM_001083334) Mouse Untagged Clone
$457.00
In Stock*
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
|---|---|
| Target Symbol | Bin1 |
| Synonyms | ALP-1; Amphl; BRAMP-2; SH3P9 |
| Vector | PCMV6-Kan/Neo |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data | |
| Restriction Sites | AscI-NotI | |
| ACCN | NM_001083334 |
| Insert Size | 1434 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution Method | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | BC065160, AAH65160 |
| RefSeq Size | 2111 bp |
| RefSeq ORF | 1434 bp |
| Locus ID | 30948 |
| Cytogenetics | 18 18.01 cM |
| Summary | Is a key player in the control of plasma membrane curvature, and membrane shaping and remodeling. Required in muscle cells for the formation of T-tubules, tubular invaginations of the plasma membrane that function in depolarization-contraction coupling. Required in muscle cells for the formation of T-tubules, tubular invaginations of the plasma membrane that function in depolarization-contraction coupling (PubMed:12183633). Is a negative regulator of endocytosis (By similarity). Is also involved in the regulation of intracellular vesicles sorting, modulation of BACE1 trafficking and the control of amyloid-beta production (PubMed:12668730, PubMed:27179792). In neuronal circuits, endocytosis regulation may influence the internalization of PHF-tau aggregates (By similarity). May be involved in the regulation of MYC activity and the control cell proliferation (By similarity).UniProtKB/Swiss-Prot Function |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
"NM_001083334" in other vectors (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| MG207643 | Bin1 (tGFP-tagged) - Mouse bridging integrator 1 (Bin1), transcript variant 2 | 10 ug |
$657.00
|
|
| MR207643 | Bin1 (Myc-DDK-tagged) - Mouse bridging integrator 1 (Bin1), transcript variant 2 | 10 ug |
$289.00
$457.00
|
|
| MR207643L3 | Lenti ORF clone of Bin1 (Myc-DDK-tagged) - Mouse bridging integrator 1 (Bin1), transcript variant 2 | 10 ug |
$757.00
|
|
| MR207643L4 | Lenti ORF clone of Bin1 (mGFP-tagged) - Mouse bridging integrator 1 (Bin1), transcript variant 2 | 10 ug |
$757.00
|
|
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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