Tor1a (NM_144884) Mouse Untagged Clone
$457.00
In Stock*
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
|---|---|
| Target Symbol | Tor1a |
| Synonyms | DQ2; Dyt1; torsinA |
| Vector | PCMV6-Kan/Neo |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data | |
| Restriction Sites | RsrII-NotI | |
| ACCN | NM_144884 |
| Insert Size | 1002 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution Method | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | BC017683, AAH17683 |
| RefSeq Size | 1397 bp |
| RefSeq ORF | 1002 bp |
| Locus ID | 30931 |
| UniProt ID | Q9ER39 |
| Cytogenetics | 2 B |
| Summary | Protein with chaperone functions important for the control of protein folding, processing, stability and localization as well as for the reduction of misfolded protein aggregates. Involved in the regulation of synaptic vesicle recycling, controls STON2 protein stability in collaboration with the COP9 signalosome complex (CSN). In the nucleus, may link the cytoskeleton with the nuclear envelope, this mechanism seems to be crucial for the control of nuclear polarity, cell movement and, specifically in neurons, nuclear envelope integrity. Participates in the cellular trafficking and may regulate the subcellular location of multipass membrane proteins such as the dopamine transporter SLC6A3, leading to the modulation of dopamine neurotransmission. In the endoplasmic reticulum, plays a role in the quality control of protein folding by increasing clearance of misfolded proteins such as SGCE variants or holding them in an intermediate state for proper refolding. May have a redundant function with TOR1B in non-neural tissues.UniProtKB/Swiss-Prot Function |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
"NM_144884" in other vectors (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| MG204930 | Tor1a (tGFP-tagged) - Mouse torsin family 1, member A (torsin A) (Tor1a) | 10 ug |
$657.00
|
|
| MR204930 | Tor1a (Myc-DDK-tagged) - Mouse torsin family 1, member A (torsin A) (Tor1a) | 10 ug |
$289.00
$457.00
|
|
| MR204930L3 | Lenti ORF clone of Tor1a (Myc-DDK-tagged) - Mouse torsin family 1, member A (torsin A) (Tor1a) | 10 ug |
$757.00
|
|
| MR204930L4 | Lenti ORF clone of Tor1a (mGFP-tagged) - Mouse torsin family 1, member A (torsin A) (Tor1a) | 10 ug |
$757.00
|
|
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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