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E Cadherin (CDH1) Mouse Monoclonal Antibody [Clone ID: UMAB184]

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SKU
UM800076
CDH1 mouse monoclonal antibody,clone UMAB184
Size:
100 ul 30 ul
Formulation:
Standard Carrier-free
Conjugation:
Unconjugated
  $610.00
In Stock*
Bulk/Customize

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View other "E Cadherin or NM_004360" antibodies

Specifications
Specifications
Product Data
Clone Name UMAB184
Application 10k-ChIP, FC, IF, IHC, WB
Recommended Dilution WB 1:500
IHC 1:50
IF 1:50
FC 1:50
Reactivity Human
Antibody Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen The extracellular domain of human CDH1 (NP_004351) produced in human cells.
Buffer PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide
Concentration 0.5~1.0 mg/ml (Lot Dependent)
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Predicted Protein Size 94.8 kDa
Gene Name cadherin 1
Database Link
Background This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function is thought to contribute to progression in cancer by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. Identified transcript variants arise from mutation at consensus splice sites. provided by RefSeq, Jul 2008
Synonyms Arc-1; CD324; CDHE; ECAD; LCAM; UVO
Reference Data
Protein Categories Cancer: Endocrine, Cancer: Gastrointestinal, Cancer: Gynecologic, Cancer: Head and Neck, CD Markers, Membrane Proteins
Protein Families Druggable Genome, ES Cell Differentiation/IPS, Transmembrane
Protein Pathways Adherens junction, Bladder cancer, Cell adhesion molecules (CAMs), Endometrial cancer, Melanoma, Pathogenic Escherichia coli infection, Pathways in cancer, Thyroid cancer
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Other "UMAB184" antibodies (2)
SKU Description Size Price
UM800076CF Carrier-free (BSA/glycerol-free) CDH1 mouse monoclonal antibody,clone UMAB184 100 ug
$680.00
UM870076 CDH1 mouse monoclonal antibody,clone UMAB184 30 ul
$224.00

file-alt Citations

Intrauterine hCG application increases expression of endothelial cell-cell adhesion molecules in human
Bienert, Habib, Buck et al
Arch Gynecol Obstet (2021)
Cited by 11
AI Summary: OriGene’s mouse anti-human E-Cadherin antibody was used in this study to identify and analyze epithelial cell populations in endometrial tissue, contributing to the assessment of cell-type specific responses to intrauterine hCG application.
Snippet: Antibodies for the epithelial cell cluster were mouse anti-human E-Cadherin as primary antibody (Origene) with the secondary antibody FITC goat anti-mouse (BD Bioscience) and rabbit anti-human Desmocollin 2 as the primary antibody (Progen) with the secondary;- Antibodies for the epithelial cell cluster were mouse anti-human E-Cadherin as primary antibody (Origene) with the secondary antibody FI...
FC
ATF5 involved in radioresistance in nasopharyngeal carcinoma by promoting epithelial-to-mesenchymal phenotype transition
Shuai, Fan, Zhong et al
Eur Arch Otorhinolaryngol (2020)
Cited by 9
AI Summary: OriGene products, specifically the mouse monoclonal anti-E-cadherin and rabbit monoclonal anti-N-cadherin antibodies, were used to assess changes in epithelial and mesenchymal marker expression, helping to elucidate the role of ATF5 in promoting epithelial-to-mesenchymal transition and radioresistance in nasopharyngeal carcinoma cells.
Snippet: Cells were then incubated overnight at 4 °C with the following antibodies: rabbit monoclonal anti-ATF5 (Abcam, 1:200 dilution, Massachusetts, US), mouse monoclonal anti-E-cadherin (Origene, 1:200 dilution, Rockville, US), rabbit monoclonal anti-N-cadherin (Ori
WB
Cathepsin B defines leader cells during the collective invasion of salivary adenoid cystic carcinoma
Wu, Li, Wang et al
Int J Oncol (2019) 54 (4), 1233-1244 DOI: 10.3892/ijo.2019.4722
Cited by 36
AI Summary: OriGene products contributed to this study by providing the CTSB-specific siRNA (OriGene, SR307305) used to knock down Cathepsin B expression in SACC-83 cells, enabling the researchers to investigate the role of CTSB in cell migration, invasion, and leader cell formation.
FigureFigureFigure
Cathepsin B defines leader cells during the collective invasion of salivary adenoid cystic carcinoma
Wu, Li, Wang et al
Int J Oncol (2019)
AI Summary: OriGene products, specifically the rabbit anti-E-cadherin (UM870076), mouse anti-N-cadherin (UM500023), and rabbit anti-vimentin antibodies, were used in this study to detect key proteins involved in cell adhesion and epithelial-mesenchymal transition, helping to elucidate the role of Cathepsin B in collective invasion of salivary adenoid cystic carcinoma.
Snippet: …UM870076;OriGene Technologies, Inc., Shanghai, China);mouse anti-N-cadherin, 1:200 (cat. … UM500023;OriGene Technologies, Inc.);rabbit anti-vimentin, 1:200 (cat. …UM870076;mouse anti‑N‑cadherin, 1:200 (cat. … UM500023;rabbit anti‑vimentin, 1:200 (cat. …
Macrophages significantly enhance wound healing in a vascularized skin model
Kreimendahl, Marquardt, Apel et al
J Biomed Mater Res A (2019)
AI Summary: Based on the provided abstract and snippet, there is no direct mention of any OriGene products or their contribution to the study "Macrophages significantly enhance wound healing in a vascularized skin model," and thus no OriGene products can be summarized as having contributed to this paper.
Snippet: stained by applying a rabbit anti-human pan-cytokeratin primary antibody (1:100;Acris Antibodies) and an Alexa Fluor 488 goat anti-rabbit IgG secondary antibody (1:400, Thermo using a rabbit anti-human collagen IV primary antibody (1:100, Acris Antibodies) labelled
IF
Prediction model of lymphovascular invasion based on clinicopathological factors in Chinese patients with invasive breast cancer
Shen, Wu, Xiao et al
Medicine (Baltimore) (2018) 97 (43), e12973 DOI: 10.1097/MD.0000000000012973
Cited by 18
AI Summary: OriGene products, specifically the anti-HER-2 antibody (TA808229), anti-Ki67 antibody (TA500294), and anti-P53 antibody (TA802901), were used for immunohistochemical detection of protein expression in breast cancer tissue samples, contributing to the evaluation of clinicopathological risk factors for lymphovascular invasion in this study.
FigureFigureFigure
Showing 1-6 of 9 papers.
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