ZP2 (NM_003460) Human Recombinant Protein

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SKU
TP319115
Recombinant protein of human zona pellucida glycoprotein 2 (sperm receptor) (ZP2), 20 µg
  $737.00
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Specifications
Specifications
Product Data
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence
Protein Sequence
>RC219115 representing NM_003460
Red=Cloning site Green=Tags(s)

MACRQRGGSWSPSGWFNAGWSTYRSISLFFALVTSVNSIDVSQLVNPAFPGTVTCDEREITVEFPSSPGT
KKWHASVVDPLGLDMPNCTYILDPEKLTLRATYDNCTRRVHGGHQMTIRVMNNSAALRHGAVMYQFFCPA
MQVEETQGLSASTICQKDFMSFSLPRVFSGLADDSKGTKVQMGWSIEVGDGARAKTLTLPEAMKEGFSLL
IDNHRMTFHVPFNATGVTHYVQGNSHLYMVSLKLTFISPGQKVIFSSQAICAPDPVTCNATHMTLTIPEF
PGKLKSVSFENQNIDVSQLHDNGIDLEATNGMKLHFSKTLLKTKLSEKCLLHQFYLASLKLTFLLRPETV
SMVIYPECLCESPVSIVTGELCTQDGFMDVEVYSYQTQPALDLGTLRVGNSSCQPVFEAQSQGLVRFHIP
LNGCGTRYKFEDDKVVYENEIHALWTDFPPSKISRDSEFRMTVKCSYSRNDMLLNINVESLTPPVASVKL
GPFTLILQSYPDNSYQQPYGENEYPLVRFLRQPIYMEVRVLNRDDPNIKLVLDDCWATSTMDPDSFPQWN
VVVDGCAYDLDNYQTTFHPVGSSVTHPDHYQRFDMKAFAFVSEAHVLSSLVYFHCSALICNRLSPDSPLC
SVTCPVSSRHRRATGATEAEKMTVSLPGPILLLSDDSSFRGVGSSDLKASGSSGEKSRSETGEEVGSRGA
MDTKGHKTAGDVGSKAVAAVAAFAGVVATLGFIYYLYEKRTVSNH

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag C-Myc/DDK
Predicted MW 78.2 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol
Preparation Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_003451
Locus ID 7783
UniProt ID Q05996
Cytogenetics 16p12.3-p12.2
RefSeq Size 2266
RefSeq ORF 2235
Synonyms OOMD6; Zp-2; ZPA
Summary The zona pellucida is an extracellular matrix that surrounds the oocyte and early embryo. It is composed of three glycoproteins with various functions during fertilization and preimplantation development. The glycosylated mature peptide is one of the structural components of the zona pellucida and functions in secondary binding and penetration of acrosome-reacted spermatozoa. Female mice lacking this gene do not form a stable zona matrix and are sterile. Alternative splicing results in multiple transcript variants. provided by RefSeq, Feb 2014
Protein Categories Membrane Proteins, Secreated Proteins
Protein Families Secreted Protein, Transmembrane
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Documents
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Other "ZP2" proteins (3)
SKU Description Size Price
PH319115 ZP2 MS Standard C13 and N15-labeled recombinant protein (NP_003451) 10 ug
$3,360.00
LC418662 Lyophilized ZP2 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY418662 Transient overexpression lysate of zona pellucida glycoprotein 2 (sperm receptor) (ZP2) (as WB positive control) 100 ug
$665.00

file-alt Citations

Human-specific features of the cerebellum and ZP2-regulated synapse development
Kim, Cherskov, Sindhwani et al
Cell (2026) 189 (6), 1802-1819.e28 DOI: 10.1016/j.cell.2026.02.014
Cited by 2
AI Summary: OriGene’s Human Recombinant ZP2 protein (Cat# TP319115) and Mouse Recombinant ZP2 protein (Cat# TP510212) were used in this study to investigate the role of ZP2 in human cerebellar synapse development and its evolutionary specialization.
Snippet: Human Recombinant ZP2 protein OriGene Cat# TP319115 Mouse Recombinant ZP2 protein OriGene Cat# TP510212
Showing 1-1 of 1 papers.
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