SRRM4 (NM_194286) Human Tagged ORF Clone
$853.00
In Stock*
Specifications
| Product Data | |
| Type | Human Tagged ORF Clone |
|---|---|
| Target Symbol | SRRM4 |
| Synonyms | KIAA1853; MU-MB-2.76; nSR100 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data | |
| Chromatograms |
Chromatograms
 Sequencher program is needed, download here |
| Restriction Sites |
SgfI-MluI Cloning Scheme for this gene
|
Plasmid Map
|
| ACCN | NM_194286 |
| ORF Size | 1833 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution Method | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | NM_194286.4 |
| RefSeq Size | 8494 bp |
| RefSeq ORF | 1836 bp |
| Locus ID | 84530 |
| UniProt ID | A7MD48 |
| Cytogenetics | 12q24.23 |
| MW | 69 kDa |
| Summary | SRRM4 promotes alternative splicing and inclusion of neural-specific exons in target mRNAs (Calarco et al., 2009 PubMed 19737518).supplied by OMIM, Oct 2009 |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
"NM_194286" in other vectors (6)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| RC219268L1 | Lenti-ORF clone of SRRM4 (Myc-DDK-tagged)-Human serine/arginine repetitive matrix 4 (SRRM4) | 10 ug |
$1,153.00
|
|
| RC219268L2 | Lenti-ORF clone of SRRM4 (mGFP-tagged)-Human serine/arginine repetitive matrix 4 (SRRM4) | 10 ug |
$1,153.00
|
|
| RC219268L3 | Lenti-ORF clone of SRRM4 (Myc-DDK-tagged)-Human serine/arginine repetitive matrix 4 (SRRM4) | 10 ug |
$1,153.00
|
|
| RC219268L4 | Lenti-ORF clone of SRRM4 (mGFP-tagged)-Human serine/arginine repetitive matrix 4 (SRRM4) | 10 ug |
$1,153.00
|
|
| RG219268 | SRRM4 (tGFP-tagged) - Human serine/arginine repetitive matrix 4 (SRRM4) | 10 ug |
$1,053.00
|
|
| SC314194 | SRRM4 (untagged)-Human serine/arginine repetitive matrix 4 (SRRM4) | 10 ug |
$911.00
|
|
Citations
Autism-related traits in myotonic dystrophy type 1 model mice are due to MBNL sequestration and RNA mis-splicing of autism-risk genes
Sznajder, Khan, Ciesiołka et al
Nat Neurosci (2025)
Sznajder, Khan, Ciesiołka et al
Nat Neurosci (2025)
Cited by 17
Alternative splicing of LSD1+8a in neuroendocrine prostate cancer is mediated by SRRM4
Coleman, Sampson, Sehrawat et al
Neoplasia (2020) 22 (6), 253-262 DOI: 10.1016/j.neo.2020.04.002
Coleman, Sampson, Sehrawat et al
Neoplasia (2020) 22 (6), 253-262 DOI: 10.1016/j.neo.2020.04.002
Cited by 29
AI Summary: OriGene’s pCMV6-SRRM4 plasmid (Cat No. RC219268) was used in this study to overexpress SRRM4 in cell lines, enabling the authors to investigate SRRM4’s role in mediating alternative splicing of LSD1+8a in neuroendocrine prostate cancer.
Snippet: … A constitutively overexpressing FLAG-SRRM4 plasmid (pCMV6-SRRM4) was obtained from Origene (Cat No. RC219268). …A constitutively overexpressing FLAG-SRRM4 plasmid (pCMV6-SRRM4) was obtained from Origene (Cat No. RC219268). …A constitutively overexpressing FLAG-SRRM4 plasmid (pCMV6-SRRM4) was obtained from Origene (Cat No. RC219268). …
Showing 1-2 of 2 papers.
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