Egr2 (NM_010118) Mouse Tagged Lenti ORF Clone
- LentiORF®
SKU
MR227610L2
Lenti ORF clone of Egr2 (mGFP-tagged) - Mouse early growth response 2 (Egr2)
$986.00
3 Weeks*
Specifications
| Product Data | |
| Type | Mouse Tagged ORF Clone |
|---|---|
| Target Symbol | Egr2 |
| Synonyms | Egr-2; Krox-20; Krox20; NGF1-B; Zfp-6; Zfp-25 |
| Vector | pLenti-C-mGFP |
| E. coli Selection | Chloramphenicol (34 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data | |
| Restriction Sites |
SgfI-MluI Cloning Scheme for this gene
|
Plasmid Map
|
| ACCN | NM_010118 |
| ORF Size | 1410 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution Method | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | NM_010118.3, NP_034248.2 |
| RefSeq Size | 2972 bp |
| RefSeq ORF | 1413 bp |
| Locus ID | 13654 |
| UniProt ID | P08152 |
| Cytogenetics | 10 34.96 cM |
| Summary | Sequence-specific DNA-binding transcription factor. Binds to two specific DNA sites located in the promoter region of HOXA4. Binds to the promoter region of ERBB2. May play a role in the regulation of hindbrain segmentation, might act in combination with the Hox network to specify odd and even rhombomeres, and might participate in the control of the expression of some of the homeobox containing genes.UniProtKB/Swiss-Prot Function |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
"NM_010118" in other vectors (6)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| MC216445 | Egr2 (untagged) - Mouse early growth response 2 (Egr2), (10ug) | 10 ug |
$503.00
|
|
| MG227610 | Egr2 (tGFP-tagged) - Mouse early growth response 2 (Egr2), (10ug) | 10 ug |
$886.00
|
|
| MR227610 | Egr2 (Myc-DDK-tagged) - Mouse early growth response 2 (Egr2) | 10 ug |
$686.00
|
|
| MR227610L1 | Lenti ORF clone of Egr2 (Myc-DDK-tagged) - Mouse early growth response 2 (Egr2) | 10 ug |
$986.00
|
|
| MR227610L3 | Lenti ORF clone of Egr2 (Myc-DDK-tagged) - Mouse early growth response 2 (Egr2) | 10 ug |
$986.00
|
|
| MR227610L4 | Lenti ORF clone of Egr2 (mGFP-tagged) - Mouse early growth response 2 (Egr2) | 10 ug |
$986.00
|
|
Citations
Disruption of Krox20-Notch1 signaling blocks meibomian gland development and homeostasis leading to dry eye disease
Zhang, Tchegnon, Ghotbi et al
Nat Commun (2025)
Zhang, Tchegnon, Ghotbi et al
Nat Commun (2025)
Cited by 3
AI Summary: OriGene’s pLenti-KROX20 (Krox20-myc-flag, MR227610L2) lentiviral plasmid was used to overexpress KROX20 in meibomian gland epithelial cells, enabling the study of Krox20’s role in gland development and homeostasis in this research.
Snippet: PAX2 (12260, Addgene), pMD2.G (12259, Addgene), and pLenti-KROX20 (Krox20-myc-flag (MR227610L2, OriGene) was cloned into pLenti-CMV-Puro) or pLenti-GFP (17448, Addgene). IHMGECs were transduced with the generated lentivirus upon 30% confluency, and the mRNA and protein p
Showing 1-1 of 1 papers.
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complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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