TissueScan, Melanoma cDNA Array I

SKU
MERT501
TissueScan Melanoma Tissue qPCR Panel I (10) containing ten identical sets of 43 tissues covering four disease stages and normal tissues
  $2,500.00
In Stock*
Specifications
Specifications
Product Data
TissueScan Type Cancer Specific
Array Name Melanoma cDNA Array I
Clinical Info
Diagnosis Category Melanoma
Tissue Skin, Anus, Eye
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Description TissueScan Melanoma Tissue qPCR Panel I (10) containing ten identical sets of 43 tissues covering four disease stages and normal tissues
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Low expression of the PPARγ-regulated gene thioredoxin-interacting protein accompanies human melanoma progression and promotes experimental lung metastases
Meylan, Pich, Winkler et al
Sci Rep (2021) 11 (1), 7847 DOI: 10.1038/s41598-021-86329-5
Cited by 29
AI Summary: OriGene’s human melanoma tissue microarray (MERT501) was used in this study to analyze TXNIP expression across different melanoma disease stages and normal tissues, contributing to the investigation of TXNIP’s role in melanoma progression and metastasis.
Snippet: MERT501) containing ten identical sets of 43 tissues covering four disease stages (1 × Stage IIIA, 6 × IIIB, 4 × IIIC, 10 × III 19 × IV) and normal tissues was purchased from OriGene. Cell culture and treatments Human melanoma cell lines A375 (CLS Cat# 300110/p852_A-375, RRID:CVCL_0132) and C8161 (RRID:CVCL_6813;kindly provided by Prof. D. Constam, EPFL, Lausanne, Switze
FigureFigureFigure
Induction of paracrine signaling in metastatic melanoma cells by PPARγ agonist rosiglitazone activates stromal cells and enhances tumor growth
Pich, Meylan, Mastelic-Gavillet et al
Cancer Res. (2018)
AI Summary: OriGene's Melanoma cDNA array (#MERT501) was used in this study to analyze gene expression profiles across different melanoma stages, aiding in the investigation of rosiglitazone-induced paracrine signaling in melanoma cells.
Snippet: Melanoma cDNA array containing sets of 43 melanoma tumors surgically-resected from patients, covering four disease stages (21 stage III, 19 stage IV) was purchased from OriGene (#MERT501, Herford, Germany). cDNA extracted from primary melanocytes from four
Modulation of extracellular matrix/adhesion molecule expression by BRG1 is associated with increased melanoma invasiveness
Saladi, Keenen, Marathe et al
Mol Cancer (2010) 9, 280 DOI: 10.1186/1476-4598-9-280
Cited by 74
AI Summary: In this study, OriGene’s BRG1 expression plasmid (RC200125) and BRG1 shRNA (TF312908) were used to manipulate BRG1 levels in melanoma cells, enabling the authors to investigate how BRG1 regulates extracellular matrix and adhesion molecule expression and contributes to increased melanoma invasiveness.
FigureFigureFigure
CAV1 inhibits metastatic potential in melanomas through suppression of the integrin/Src/FAK signaling pathway
Trimmer, Whitaker-Menezes, Bonuccelli et al
Cancer Res (2010) 70 (19), 7489-99 DOI: 10.1158/0008-5472.CAN-10-0900
AI Summary: OriGene products contributed to this study by providing the CAV1 expression plasmid (OriGene, Cat# SC116167), which was used to generate B16F10 melanoma cells overexpressing CAV1 for functional analyses of tumor growth and metastasis.
FigureFigure
Showing 1-4 of 4 papers.
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