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TissueScan, Ovarian Cancer cDNA Array IV

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SKU
HORT104
48 samples covering 6-normal, 5-Stage IA, 1-IB, 1-IC, 1-IIB, 4-IIIA, 6-IIIB, 21-IIIC, 2-III, 1-IV. Available in 2, 5, 10 identical plates.
  $1,060.00
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Specifications
Specifications
Product Data
TissueScan Type Cancer Specific
Array Name Ovarian Cancer cDNA Array IV
Clinical Info
Diagnosis Category Ovarian Cancer
Tissue Ovary
Shipping Ambient
Description 48 samples covering 6-normal, 5-Stage IA, 1-IB, 1-IC, 1-IIB, 4-IIIA, 6-IIIB, 21-IIIC, 2-III, 1-IV. Available in 2, 5, 10 identical plates.
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Documents
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Hedgehog/GLI1 Transcriptionally Regulates FANCD2 in Ovarian Tumor Cells: Its Inhibition Induces HR-Deficiency and Synergistic Lethality with PARP Inhibition
Mani, Tripathi, Chaudhary et al
Neoplasia (2021) 23 (9), 1002-1015 DOI: 10.1016/j.neo.2021.06.010
Cited by 17
AI Summary: In this study, the OriGene GLI1 (Myc-tagged) plasmid (Cat No: RC201110) was used to overexpress GLI1 in ovarian tumor cells, enabling the investigation of GLI1's role in regulating FANCD2 and its impact on DNA repair and sensitivity to PARP inhibition.
Snippet: UCCACUCU) [10]. For GLI1 down-regulation, the data using siGLI1-5 sequences were presented in these studies unless otherwise mentioned. GLI1 (Myc- tagged) plasmid (Cat No: RC201110) was procured from Origene and transfected using Lipofectamine 2000 according to the manufacturer's protocols. Colony assay For experiments using siRNA knockdown, 48 hours after siGLI1 or siControl transfection, cells
FigureFigureFigure
Inhibition of Transient Receptor Potential Vanilloid 6 channel, elevated in human ovarian cancers, reduces tumour growth in a xenograft model
Xue, Wang, MacCormack et al
J Cancer (2018) 9 (17), 3196-3207 DOI: 10.7150/jca.20639
Cited by 53
AI Summary: OriGene products, specifically the TRPV6 antibody (Cat# TA326183) and TRPV6 qPCR primer set (Cat# HP208799), were used in this study to detect and quantify TRPV6 mRNA and protein levels in ovarian cancer tissues and cell lines, enabling the researchers to demonstrate elevated TRPV6 expression and assess the effects of TRPV6 inhibition on tumor growth.
FigureFigureFigure
The serine protease prostasin (PRSS8) is a potential biomarker for early detection of ovarian cancer
Tamir, Gangadharan, Balwani et al
J Ovarian Res (2016) 9, 20 DOI: 10.1186/s13048-016-0228-9
Cited by 42
AI Summary: OriGene products, including the PRSS8 cDNA clone and PRSS8-specific qRT-PCR primers, were used in this study to analyze and confirm PRSS8 (prostasin) gene expression levels in ovarian cancer cell lines and tissue samples.
FigureFigureFigure
Rad6 upregulation promotes stem cell-like characteristics and platinum resistance in ovarian cancer
Somasagara, Tripathi, Spencer et al
Biochem. Biophys. Res. Commun. (2015)
Cited by 30
AI Summary: OriGene’s HORT104 ovarian cDNA array was used in this study to quantitatively analyze Rad6 and Gli1 mRNA levels across normal and tumor ovarian tissue samples, helping to establish the correlation between Rad6 expression and ovarian cancer progression.
Snippet: D. Quantitative RT-PCR of Rad6 and Gli1 mRNA levels in normal ovarian (n = 6) and graded ovarian tumors (n = 42) of the HORT104 ovarian cDNA array (OriGene). Message levels were normalized to GAPDH mRNA and quantified using the ΔΔCt method. ... Cite SaveSaving
Kallikrein family proteases KLK6 and KLK7 are potential early detection and diagnostic biomarkers for serous and papillary serous ovarian cancer subtypes
Tamir, Jag, Sarojini et al
J Ovarian Res (2014) 7 (1), 109 DOI: 10.1186/PREACCEPT-1736656869122663
AI Summary: OriGene’s TissueScan Cancer Survey Panel and OVC Panel I-IV were used for expression screening and validation of KLK6 and KLK7 biomarkers in various cancer types and ovarian cancer subtypes, supporting the identification of these genes as potential early detection markers for ovarian cancer.
Snippet: Poor quality specimens that produced no meaningful values after 40 cycles of qPCR were not included in the data processing steps. The TissueScan Cancer Survey Panel and OVC Panel I-IV (both from OriGene, Rockville, MD) were used as described by the manufacturer ... Cite SaveSaving
Rad6-Mediated Ubiquitin Signaling in the Etiology and Therapeutics of Ovarian Cancer
Spencer
Thesis (2017)
Snippet: Semi-Quantitative PCR analysis. The HORT104 ovarian cDNA panel was purchased. from OriGene. Quantitative real time polymerase chain reaction (qPCR) was used to. calculate mRNA levels of Rad6 and Gli1 in normal ovarian (n=6) and ovarian tumor. 25
Showing 1-6 of 7 papers.
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