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Gdf15 Rat shRNA Plasmid (Locus ID 29455)

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SKU
TL710232
Gdf15 - Rat, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
  $1,013.00
2 Weeks*

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Specifications
Specifications
Product Data
Locus ID 29455
Vector pGFP-C-shLenti
E. coli Selection Chloramphenicol (34 ug/ml)
Mammalian Cell Selection Puromycin
Format Lentiviral plasmids
Components Gdf15 - Rat, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 29455). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
RefSeq NM_019216, NM_019216.1, NM_019216.2
UniProt ID Q9Z0J6
Summary member of the TGF-beta superfamily of growth factors RGD, Feb 2006
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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Documents
Resources

file-alt Citations

Subregional differences in astrocytes underlie selective neurodegeneration or protection in Parkinson's disease models in culture
Kostuk, Cai, Iacovitti
Glia (2019)
AI Summary: OriGene products, specifically the GDF15 lentiviral shRNA plasmid (catalog# TL710232) and the shRNA lentiviral packaging kit (catalog# TR30037), were used to knock down GDF15 expression in astrocytes, helping to demonstrate the role of GDF15 in astrocyte-mediated neuroprotection in Parkinson's disease models.
Snippet: 2.8 Lentiviral shRNA knockdown. GDF‐15 lentiviral shRNA plasmid was purchased from Origene (catalog# TL710232, pGFP‐C‐shLenti). Lentiviral particles were prepared following manufacturers protocols (shRNA lentiviral packaging kit catalog# TR30037)
Growth differentiation factor 15 stimulates rapamycin-sensitive ovarian cancer cell growth and invasion
Griner, Joshi, Nahta
Biochem. Pharmacol. (2013) 85 (1), 46-58 DOI: 10.1016/j.bcp.2012.10.007
Cited by 71
AI Summary: OriGene’s human ovarian tumor tissue microarrays (TMA) were used for immunohistochemical analysis to assess GDF15 expression levels in ovarian cancer tissues in this study.
Snippet: IHC was performed on 2 sets of human ovarian tumor tissue microarrays (TMA) using a standard immunoperoxidase procedure. The first TMA consisted of 5 normal and 29 ovarian cancer tissues (Origene, 9620 Medical Center Dr., Suite 200, Rockville, MD 20850).
Showing 1-2 of 2 papers.
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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