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Ptk2b Rat shRNA Plasmid (Locus ID 50646)

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SKU
TL710108
Ptk2b - Rat, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
  $1,013.00
In Stock*

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Other products for "Ptk2b or NM_017318"

Specifications
Specifications
Product Data
Locus ID 50646
Synonyms CAKB; CAK beta; CAKbeta; Pyk2
Vector pGFP-C-shLenti
E. coli Selection Chloramphenicol (34 ug/ml)
Mammalian Cell Selection Puromycin
Format Lentiviral plasmids
Components Ptk2b - Rat, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 50646). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
RefSeq NM_017318, NM_017318.1, BC101921
UniProt ID P70600
Summary may phosphorylate focal adhesion kinase FAK; may play a role in actin cytoskeleton reorganization; may mediate thrombin induced astrocyte proliferation RGD, Feb 2006
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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Documents
Resources

file-alt Citations

α1-Adrenergic receptor-PKC-Pyk2-Src signaling boosts L-type Ca2+ channel CaV1.2 activity and long-term potentiation in rodents
Man, Bartels, Henderson et al
Elife (2023) 12 DOI: 10.7554/eLife.79648
AI Summary: OriGene products contributed to this study by providing HIV-GFP-Pyk2shA-D (Cat# TL710108) and HIV-GFP-SrcshA-D (Cat# TL711639) plasmids used for knocking down rat Pyk2 and Src, enabling the researchers to investigate the roles of these kinases in α1-adrenergic receptor signaling and CaV1.2 channel regulation.
Snippet: isualize infection. All HIV plasmids (HIV-GFP-Pyk2shA-D;HIV-GFP-SrcshA-D) for knocking down rat Pyk2 or Src as well as the scrambled, non-silencing hairpin control (HIV-GFP-shscr) were obtained from Origene (Cat# TL710108 and #TL711639). All expression plasmids (listed in Supplementary file 4) were confirmed by DNA sequencing. Production of lentivirus for Pyk2 and Src knockdown HEK293T/17 (ATCC
FigureFigureFigure
Showing 1-1 of 1 papers.
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