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Grhl2 Rat shRNA Plasmid (Locus ID 299979)

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SKU
TL708667
Grhl2 - Rat, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
  $1,013.00
2 Weeks*

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Specifications
Specifications
Product Data
Locus ID 299979
Synonyms RGD1561191
Vector pGFP-C-shLenti
E. coli Selection Chloramphenicol (34 ug/ml)
Mammalian Cell Selection Puromycin
Format Lentiviral plasmids
Components Grhl2 - Rat, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 299979). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
RefSeq NM_001134527, NM_001134527.1, BC168688
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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Documents
Resources

file-alt Citations

Grainyhead-like 2 (GRHL2) knockout abolishes oral cancer development through reciprocal regulation of the MAP kinase and TGF-β signaling pathways
Chen, Kang, Alshaikh et al
Oncogenesis (2018) 7 (5), 38 DOI: 10.1038/s41389-018-0047-5
AI Summary: OriGene’s GRHL2 shRNA vectors (ShGRHL2-1, -2, -3) were used to knock down GRHL2 expression in oral squamous cell carcinoma cell lines, enabling the study to investigate the effects of GRHL2 loss on MAP kinase and TGF-β signaling pathways in oral cancer development.
Snippet: al vector (LV-ShContr), as described previously4,20. GRHL2 was also knocked down in SCC15 and BaP-T cells using commercial GRHL2 shRNA vectors (ShGRHL2-1, -2, -3) targeting different Grhl2 sequences (Origene, Rockville, MD). Generation of Grhl2 cKO mice Epithelial tissue-specific Grhl2 cKO mice (denoted K14/Grhl2 cKO) were generated by crossing Grhl2 floxed (fl/fl) mice48 with the K14-CreERT mice
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Showing 1-1 of 1 papers.
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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