Spocd1 - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 622480). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
Essential excecutor of PIWIL4-piRNA pathway directed transposon DNA methylation and silencing in the male embryonic germ cells (PubMed:32674113). Associates with the de novo DNA methylation machinery and repressive chromatin remodeling complexes (PubMed:32674113). Tethering of PIWIL4 to a nascent transposable element transcript recruits repressive chromatin remodeling activities and the de novo methylation apparatus through SPOCD1 (PubMed:32674113). Not required for piRNA biosynthesis (PubMed:32674113).UniProtKB/Swiss-Prot Function
shRNA Design
These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
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