Arpp19 Mouse shRNA Plasmid (Locus ID 59046)
Specifications
| Product Data | |
| Locus ID | 59046 |
|---|---|
| Synonyms | 19kDa; 2700024H10Rik; ARPP-19; Arpp12; AW559096 |
| Vector | pGFP-C-shLenti |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Lentiviral plasmids |
| Components | Arpp19 - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 59046). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free. |
| RefSeq | BC040206, NM_001142655, NM_021548, NM_001357878, NM_001357879, NM_001357880, NM_001357881, NR_152135, NM_021548.1, NM_021548.2, NM_021548.3, NM_021548.4, NM_001142655.1 |
| UniProt ID | P56212 |
| Summary | Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis. When phosphorylated at Ser-62 during mitosis, specifically interacts with PPP2R2D (PR55-delta) and inhibits its activity, leading to inactivation of PP2A, an essential condition to keep cyclin-B1-CDK1 activity high during M phase. May indirectly enhance GAP-43 expression by binding to the NGF-regulatory region of its mRNA (By similarity).UniProtKB/Swiss-Prot Function |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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