Dram2 Mouse shRNA Plasmid (Locus ID 67171)

SKU
TL516335
Dram2 - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
  $1,013.00
2 Weeks*
Specifications
Specifications
Product Data
Locus ID 67171
Synonyms 2010305N14Rik; 2610318G18Rik; AI647667; Tmem77
Vector pGFP-C-shLenti
E. coli Selection Chloramphenicol (34 ug/ml)
Mammalian Cell Selection Puromycin
Format Lentiviral plasmids
Components Dram2 - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 67171). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
RefSeq BC024458, NM_001025582, NM_001286986, NM_001286987, NM_026013, NM_001025582.1, NM_001025582.2, NM_026013.1, NM_026013.2, NM_026013.3, NM_001286986.1, NM_001286987.1
UniProt ID Q9CR48
Summary Plays a role in the initiation of autophagy. In the retina, might be involved in the process of photoreceptor cells renewal and recycling to preserve visual function. Induces apoptotic cell death when coexpressed with DRAM1.UniProtKB/Swiss-Prot Function
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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Documents
Resources

file-alt Citations

DRAM2 acts as an oncogene in non-small cell lung cancer and suppresses the expression of p53
Wudu, Ren, Hui et al
J. Exp. Clin. Cancer Res. (2019) 38 (1), 72 DOI: 10.1186/s13046-019-1068-4
AI Summary: OriGene products, specifically the DRAM2 expression plasmid, TP53 expression plasmid, and the corresponding empty pcmv6 vector, were used to manipulate gene expression in NSCLC cells, enabling the study of DRAM2’s oncogenic role and its interaction with p53 in this research.
Snippet: siRNA sequences for DRAM2 was GGACTGATTTAGAACAGAA.For DRAM2 overexpression, cells were transfected with a DRAM2 expression plasmid, TP53 expression plasmid, and the corresponding empty pcmv6 vector, which were all purchased from Origene Cached
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Showing 1-1 of 1 papers.
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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