Gabrg2 Mouse shRNA Plasmid (Locus ID 14406)

SKU TL515175

Gabrg2 - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided

Product Data

• Locus ID: 14406
• Synonyms: GABAA-R; Gabrg-2; gamma2
• Vector: pGFP-C-shLenti
• E. coli Selection: Chloramphenicol (34 ug/ml)
• Format: Lentiviral plasmids
• Components: Gabrg2 - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 14406). 5µg purified plasmid DNA per construct; 29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
• RefSeq: BC031762, NM_008073, NM_177408, NM_008073.1, NM_008073.2, NM_008073.3, NM_177408.1, NM_177408.2, NM_177408.3, NM_177408.4, NM_177408.5, NM_177408.6, NM_001362655, NM_001362656, NM_177408.7, NM_008073.4
• UniProt ID: P22723
• Summary: This gene encodes a gamma-aminobutyric acid (GABA)-A receptor subunit, which is a member of the ligand-gated ion channel family. GABA is the major inhibitory neurotransmitter in the adult central nervous system, and conversely exhibits an excitatory function during development. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. This gene encodes one of three gamma subunits in mammals, which contain the binding site for benzodiazepine drugs. Several mutations in this gene are associated with epileptic seizures, and genetic knockdown is associated with anxiety behavior. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013]
• shRNA Design: These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
• Shipping: Ambient