Mcmbp Mouse shRNA Plasmid (Locus ID 210711)
Specifications
| Product Data | |
| Locus ID | 210711 |
|---|---|
| Synonyms | 1110007A13Rik; AU017382; BC025641; MCM-BP |
| Vector | pGFP-C-shLenti |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Lentiviral plasmids |
| Components | Mcmbp - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 210711). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free. |
| RefSeq | BC025641, BC038342, NM_145955, NM_145955.1, NM_145955.2, NM_145955.3 |
| UniProt ID | Q8R3C0 |
| Summary | Associated component of the MCM complex that acts as a regulator of DNA replication. Binds to the MCM complex during late S phase and promotes the disassembly of the MCM complex from chromatin, thereby acting as a key regulator of pre-replication complex (pre-RC) unloading from replicated DNA. Can dissociate the MCM complex without addition of ATP; probably acts by destabilizing interactions of each individual subunits of the MCM complex. Required for sister chromatid cohesion (By similarity).UniProtKB/Swiss-Prot Function |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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