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Trpc6 Mouse shRNA Plasmid (Locus ID 22068)

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SKU
TL514996
Trpc6 - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
  $1,013.00
In Stock*

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Other products for "Trpc6 or NM_001282086"

Specifications
Specifications
Product Data
Locus ID 22068
Synonyms AV025995; LLHWJM002; LLHWJM003; LLHWJM004; mtrp6; TRP-6; Trrp6
Vector pGFP-C-shLenti
E. coli Selection Chloramphenicol (34 ug/ml)
Mammalian Cell Selection Puromycin
Format Lentiviral plasmids
Components Trpc6 - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 22068). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
RefSeq NM_001282086, NM_001282087, NM_013838, NM_013838.1, NM_013838.2, NM_001282087.1, NM_001282086.1, BC141131, BC067391, BC068310
UniProt ID Q61143
Summary Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Activated by diacylglycerol (DAG) in a membrane-delimited fashion, independently of protein kinase C. Seems not to be activated by intracellular calcium store depletion.UniProtKB/Swiss-Prot Function
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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Documents
Resources

file-alt Citations

Englerin A Agonizes the TRPC4/C5 Cation Channels to Inhibit Tumor Cell Line Proliferation
Carson, Raman, Tullai et al
PLoS ONE (2015) 10 (6), e0127498 DOI: 10.1371/journal.pone.0127498
Cited by 109
AI Summary: In this study, the human TRPC4 cDNA obtained from OriGene (catalog number RC218941) was used to construct HEK293T cell lines with inducible TRPC4 expression, enabling the researchers to investigate the role of TRPC4 in mediating the anti-proliferative effects of Englerin A on tumor cells.
Snippet: The HEK293T cell line with Dox-inducible expression of TRPC4 was constructed using the Invitrogen pcDNA5/FRT/TO TOPO TA expression kit (K6020-20). Human TRPC4 was ordered from Origene (Origene;RC218941). Forward ... Cite SaveSaving
FigureFigureFigure
Showing 1-1 of 1 papers.
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