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Cxcr2 Mouse shRNA Plasmid (Locus ID 12765)

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SKU
TL513602
Cxcr2 - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
  $1,013.00
2 Weeks*

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Specifications
Specifications
Product Data
Locus ID 12765
Synonyms CD128; CDw128; Cmkar2; Gpcr16; IL-8rb; IL-8Rh; IL8RA; Il8rb; mIL-8RH
Vector pGFP-C-shLenti
E. coli Selection Chloramphenicol (34 ug/ml)
Mammalian Cell Selection Puromycin
Format Lentiviral plasmids
Components Cxcr2 - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 12765). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
RefSeq BC051677, NM_009909, NM_009909.1, NM_009909.2, NM_009909.3
UniProt ID P35343
Summary Receptor for interleukin-8 which is a powerful neutrophil chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. Binds to IL-8 with high affinity. Also binds with high affinity to CXCL3, GRO/MGSA and NAP-2.UniProtKB/Swiss-Prot Function
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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Documents
Resources

file-alt Citations

Osteocytes support bone metastasis of melanoma cells by CXCL5
Jia, Zhang, Meng et al
Cancer Lett (2024) 590, 216866 DOI: 10.1016/j.canlet.2024.216866
Cited by 7
AI Summary: OriGene’s shCXCR2 shRNAs (Cat. #TL513602) were used in this study to down-regulate CXCR2 expression in melanoma cells, enabling the authors to demonstrate the role of the CXCL5-CXCR2 pathway in osteocyte-supported bone metastasis.
Snippet: fic shRNAs against CXCR2 (shCXCR2) and negative control (shNC) were obtained from Origene (Cat. #TL513602), Specific shRNAs against CXCL5 (shCXCL5) and negative control (shNC) were obtained from VectorBuilder (Cat. # Ecoli(VB900060-4276fjh) for shRNA1;Ecoli(VB900060-4283ufk) for shRNA2;Ecoli(VB900060-4289kxk) for shRNA3;Ecoli(VB010000-0009mxc)-P for negative control),
Showing 1-1 of 1 papers.
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