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Avpr2 Mouse shRNA Plasmid (Locus ID 12000)

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SKU
TL513450
Avpr2 - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
  $1,013.00
2 Weeks*

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Other products for "Avpr2 or NM_001276298"

Specifications
Specifications
Product Data
Locus ID 12000
Synonyms ADHR; DI; DI1; DIR; ND; ND1; V; V2R; VPV2R
Vector pGFP-C-shLenti
E. coli Selection Chloramphenicol (34 ug/ml)
Mammalian Cell Selection Puromycin
Format Lentiviral plasmids
Components Avpr2 - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 12000). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
RefSeq BC104728, BC104729, BC104731, BC105662, NM_001276298, NM_001276299, NM_019404, NM_019404.1, NM_019404.2, NM_001276299.1, NM_001276298.1, BC107005
UniProt ID O88721
Summary This gene encodes a member of the G-protein coupled receptor 1 family and the vasopressin/oxytocin receptor subfamily. The encoded protein is an arginine vasopressin receptor which, when stimulated, activates the Gs protein/adenylyl cyclase signaling cascade and is involved in water and electrolyte homeostasis. Alternative splicing results in multiple transcript variants. provided by RefSeq, Jan 2013
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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Documents
Resources

file-alt Citations

Sensory primary cilium is a responsive cAMP microdomain in renal epithelia
Sherpa, Mohieldin, Pala et al
Sci Rep (2019) 9 (1), 6523 DOI: 10.1038/s41598-019-43002-2
AI Summary: OriGene contributed to this study by providing the AVPR2/V2R-targeting shRNA lentiviral construct (pAVP2Ra-C-shLenti, TL513450) and the shRNA lentiviral packaging kit (TR30022), which were used to genetically knock down V2R expression in kidney epithelial cells.
Snippet: vasopressin receptor type-2 (AVPR2 or V2R) targeting shRNA construct (5′-ATC GCC TTG ATG GTG TTT GTG GCA CCT GC-3′: pAVP2Ra-C-shLenti) in a lentivirus backbone vector (TL513450) was ordered from Origene. Viral particles were generated in HEK cells using shRNA lentiviral packaging kit (TR30022) and passed through a 0.45-micron filter to remove cell debris. For transduction, epithelial cells we;;Arginine vasopressin receptor type-2 (AVPR2 or V2R) targeting shRNA construct (5′-ATC GCC TTG ATG GTG TTT GTG GCA CCT GC-3′: pAVP2Ra-C-shLenti) in a lentivirus backbone vector (TL513450) was ordered from Origene
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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