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Abat Mouse shRNA Plasmid (Locus ID 268860)

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SKU
TL508059
Abat - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
  $1,013.00
2 Weeks*

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Other products for "Abat or NM_001170978"

Specifications
Specifications
Product Data
Locus ID 268860
Synonyms 9630038C02Rik; AI255750; GABA; Gabaat; Gabat; Gm9851; I54; Laibat; X61497
Vector pGFP-C-shLenti
E. coli Selection Chloramphenicol (34 ug/ml)
Mammalian Cell Selection Puromycin
Format Lentiviral plasmids
Components Abat - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 268860). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
RefSeq BC058079, BC058521, NM_001170978, NM_172961, NM_172961.1, NM_172961.2, NM_172961.3, NM_001170978.1, BC012223, BC024409, BC044056, BC082329
UniProt ID P61922
Summary The encoded gene product is responsible for catabolism of gamma-aminobutyric acid (GABA), a mostly inhibitory neurotransmitter in the central nervous system, into succinic semialdehyde. Deficiency of this encoded protein includes psychomotor retardation, hypotonia, hyperreflexia, lethargy, refractory seizures, and EEG abnormalities. Alternative splicing results in multiple transcript variants. provided by RefSeq, Jan 2010
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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Documents
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file-alt Citations

Dnmt3b ablation impairs fracture repair through upregulation of Notch pathway
Ying, Xu, Wang et al
JCI Insight (2020) 5 (3) DOI: 10.1172/jci.insight.131816
Cited by 26
AI Summary: OriGene’s Lenti-shDnmt3b (catalog TL508059V) and Lenti-shRbpjκ (catalog TL512813V) lentiviral particles were used to specifically knock down Dnmt3b and Rbpjκ expression in C3H10T1/2 cells, enabling the study of their roles in mesenchymal progenitor cell differentiation during fracture repair.
Snippet: … C3H10T1/2 cells (ATCC CCL-226) were infected with Lenti-shDnmt3b virus (multiplicity of infection [MOI] = 50, Origene, catalog TL508059V) and Lenti-shRbpjκ virus (ΜΟΙ = 50;Origene, catalog ΤL512813V), respectively, to knock down Dnmt3b and Rbpjκ expression in cells. …
Showing 1-1 of 1 papers.
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