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Wnt10a Mouse shRNA Plasmid (Locus ID 22409)

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SKU
TL502422
Wnt10a - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
  $1,013.00
In Stock*

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Specifications
Specifications
Product Data
Locus ID 22409
Vector pGFP-C-shLenti
E. coli Selection Chloramphenicol (34 ug/ml)
Mammalian Cell Selection Puromycin
Format Lentiviral plasmids
Components Wnt10a - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 22409). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
RefSeq BC014737, NM_009518, NM_009518.1, NM_009518.2
UniProt ID P70701
Summary Ligand for members of the frizzled family of seven transmembrane receptors (Probable). Functions in the canonical Wnt/beta-catenin signaling pathway. Plays a role in normal ectoderm development. Required for normal tooth development. Required for normal postnatal development and maintenance of tongue papillae and sweat ducts. Required for normal proliferation of basal cells in tongue filiform papillae, plantar epithelium and sweat ducts. Required for normal expression of keratins in tongue papillae. Required for normal expression of KRT9 in foot plant epithelium. Required for normal hair follicle function.UniProtKB/Swiss-Prot Function
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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Documents
Resources

file-alt Citations

Optimized dosing schedule based on circadian dynamics of mouse breast cancer stem cells improves the anti-tumor effects of aldehyde dehydrogenase
Matsunaga, Ogino, Hara et al
Cancer Res. (2018)
AI Summary: OriGene products, specifically the pGFP-C-shAldh3a1 and pGFP-C-shWnt10a Lenti Vectors, were used in this study to knock down Aldh3a1 and Wnt10a gene expression in mouse breast cancer cells, enabling the investigation of circadian dynamics and their impact on tumor stem cell populations and treatment efficacy.
Snippet: small hairpin (sh) ribonucleic acid (RNA) against the mouse Aldh3a1 gene (pGFP-C-shAldh3a1 Lenti Vector;Origene Technologies, Inc., Rockville, MD). After infection against the mouse Wnt10a gene (pGFP-C-shWnt10a Lenti Vector;Origene Technologies, Inc.)
Showing 1-1 of 1 papers.
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