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Usp4 Mouse shRNA Plasmid (Locus ID 22258)

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SKU
TL502380
Usp4 - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
  $1,013.00
2 Weeks*

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Specifications
Specifications
Product Data
Locus ID 22258
Synonyms F730026I20Rik; mKIAA4155; Unp
Vector pGFP-C-shLenti
E. coli Selection Chloramphenicol (34 ug/ml)
Mammalian Cell Selection Puromycin
Format Lentiviral plasmids
Components Usp4 - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 22258). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
RefSeq BC011341, NM_001311157, NM_011678, NM_011678.1, NM_011678.2, BC066180, BC066865
UniProt ID P35123
Summary Deubiquitinating enzyme that removes conjugated ubiquitin from target proteins. Deubiquitinates PDPK1. Deubiquitinates TRIM21. Deubiquitinates receptor ADORA2A which increases the amount of functional receptor at the cell surface. May regulate mRNA splicing through deubiquitination of the U4 spliceosomal protein PRPF3. This may prevent its recognition by the U5 component PRPF8 thereby destabilizing interactions within the U4/U6.U5 snRNP. May also play a role in the regulation of quality control in the ER.UniProtKB/Swiss-Prot Function
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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Documents
Resources

file-alt Citations

Selection preserves Ubiquitin Specific Protease 4 alternative exon skipping in therian mammals
Vlasschaert, Xia, Gray
Sci Rep (2016) 6, 20039 DOI: 10.1038/srep20039
Cited by 28
AI Summary: OriGene Technologies contributed to this study by providing cDNAs of the mouse USP4 exon-retained and exon-skipped isoforms, which were used to investigate their subcellular localization.
Snippet: Upland CA). Microscopy and imaging. To establish the localization of exon-retained and exon skipped isoforms of USP4, cDNAs corresponding to the mouse isoforms were obtained from Origene Technologies Inc. (Rockville ... Cite SaveSaving
FigureFigureFigure
Showing 1-1 of 1 papers.
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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