Trpc4 Mouse shRNA Plasmid (Locus ID 22066)
Specifications
| Product Data | |
| Locus ID | 22066 |
|---|---|
| Synonyms | CCE1; STRPC4; Trp4; Trrp4 |
| Vector | pGFP-C-shLenti |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Lentiviral plasmids |
| Components | Trpc4 - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 22066). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free. |
| RefSeq | BC120729, BC131915, NM_001253682, NM_001253683, NM_016984, NR_046161, NM_016984.1, NM_016984.2, NM_016984.3, NM_001253683.1, NM_001253682.1, BC057335, BC060160 |
| UniProt ID | Q9QUQ5 |
| Summary | Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Acts as a cell-cell contact-dependent endothelial calcium entry channel. Has also been shown to be calcium-selective (By similarity). May also be activated by intracellular calcium store depletion. Trpc4 deficient mice lack a store-operated calcium entry in endothelial cells.UniProtKB/Swiss-Prot Function |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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