Slit1 Mouse shRNA Plasmid (Locus ID 20562)
SKU
TL502069
Slit1 - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
$1,013.00
2 Weeks*
Specifications
| Product Data | |
| Locus ID | 20562 |
|---|---|
| Synonyms | mKIAA0813; Slil1 |
| Vector | pGFP-C-shLenti |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Lentiviral plasmids |
| Components | Slit1 - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 20562). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free. |
| RefSeq | BC057131, BC062091, NM_015748, NM_015748.1, NM_015748.2, NM_015748.3 |
| UniProt ID | Q80TR4 |
| Summary | Thought to act as molecular guidance cue in cellular migration, and function appears to be mediated by interaction with roundabout homolog receptors. During neural development involved in axonal navigation at the ventral midline of the neural tube and projection of axons to different regions (By similarity). SLIT1 and SLIT2 together seem to be essential for midline guidance in the forebrain by acting as repulsive signal preventing inappropriate midline crossing by axons projecting from the olfactory bulb.UniProtKB/Swiss-Prot Function |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
Reviews
Documents
Resources
Citations
Suppression of Slit3 induces tumor proliferation and chemoresistance in hepatocellular carcinoma through activation of GSK3β/β-catenin pathway
Ng, Chow, Man et al
BMC Cancer (2018) 18 (1), 621 DOI: 10.1186/s12885-018-4326-5
Ng, Chow, Man et al
BMC Cancer (2018) 18 (1), 621 DOI: 10.1186/s12885-018-4326-5
AI Summary: OriGene contributed to this study by providing plasmids for stable knockdown of Slit3, enabling the researchers to investigate the effects of Slit3 suppression on tumor proliferation and chemoresistance in hepatocellular carcinoma.
Snippet: 5% CO 2 and were passaged according to the manufacturer's recommendations. Plasmids for stable knockdown of Slit3 were purchased commercially (Origene). The shRNA sequence was synthesized as per the Slit3 siRNA Cached
Showing 1-1 of 1 papers.
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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