Ptpn11 Mouse shRNA Plasmid (Locus ID 19247)
SKU
TL501795
Ptpn11 - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
$1,013.00
In Stock*
Specifications
| Product Data | |
| Locus ID | 19247 |
|---|---|
| Synonyms | 2700084A17Rik; AW536184; PTP1D; PTP2C; SAP-2; SH-PTP2; SH-PTP3; SHP-2; Shp2; Syp |
| Vector | pGFP-C-shLenti |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Lentiviral plasmids |
| Components | Ptpn11 - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 19247). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free. |
| RefSeq | BC057398, BC059278, NM_001109992, NM_011202, NM_011202.1, NM_011202.2, NM_011202.3, NM_001109992.1, BC003980, BC028513, BM899214 |
| UniProt ID | P35235 |
| Summary | Acts downstream of various receptor and cytoplasmic protein tyrosine kinases to participate in the signal transduction from the cell surface to the nucleus. Positively regulates MAPK signal transduction pathway. Dephosphorylates GAB1, ARHGAP35 and EGFR. Dephosphorylates ROCK2 at 'Tyr-722' resulting in stimulatation of its RhoA binding activity. Dephosphorylates CDC73.UniProtKB/Swiss-Prot Function |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
Reviews
Documents
Resources
Citations
Matrix metalloproteinase 1: role in sarcoma biology
Jawad, Garamszegi, Garamszegi et al
PLoS One (2010) 5 (12), e14250 DOI: 10.1371/journal.pone.0014250
Jawad, Garamszegi, Garamszegi et al
PLoS One (2010) 5 (12), e14250 DOI: 10.1371/journal.pone.0014250
Cited by 23
AI Summary: In this study, OriGene’s MMP1 shRNA lentiviral particles (sc-41598-V) were used to stably silence MMP1 expression in sarcoma cell lines, enabling the authors to investigate the role of tumor cell-derived MMP1 in sarcoma progression, metastasis, and angiogenesis.
Showing 1-1 of 1 papers.
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