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Prom1 Mouse shRNA Plasmid (Locus ID 19126)

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SKU
TL501745
Prom1 - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
  $1,013.00
In Stock*

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Other products for "Prom1 or NM_001163577"

Specifications
Specifications
Product Data
Locus ID 19126
Synonyms 4932416E19Rik; AC133; CD133; Prom; Prom-1; Proml1
Vector pGFP-C-shLenti
E. coli Selection Chloramphenicol (34 ug/ml)
Mammalian Cell Selection Puromycin
Format Lentiviral plasmids
Components Prom1 - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 19126). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
RefSeq BC028286, NM_001163577, NM_001163578, NM_001163581, NM_001163582, NM_001163583, NM_001163584, NM_001163585, NM_008935, NM_001163585.1, NM_008935.1, NM_008935.2, NM_001163577.1, NM_001163578.1, NM_001163581.1, NM_001163582.1, NM_001163583.1, NM_001163584.1
UniProt ID O54990
Summary May play a role in cell differentiation, proliferation and apoptosis. Binds cholesterol in cholesterol-containing plasma membrane microdomains and may play a role in the organization of the apical plasma membrane in epithelial cells. During early retinal development acts as a key regulator of disk morphogenesis (PubMed:19228982). Involved in regulation of MAPK and Akt signaling pathways. In neuroblastoma cells suppresses cell differentiation such as neurite outgrowth in a RET-dependent manner.UniProtKB/Swiss-Prot Function
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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Documents
Resources

file-alt Citations

CD133 Promotes Adhesion to the Ovarian Cancer Metastatic Niche
Roy, Bobbs, Sattler et al
Cancer Growth Metastasis (2018) 11, 1179064418767882 DOI: 10.1177/1179064418767882
Snippet: red fluorescent protein (RFP) (GenTarget;San Diego, CA, USA) ARID3B (pLenti-CMV;GenTarget), PROM1 (pReceiver-LV122;GeneCopeia), or short hairpin RNA (shRNA) targeted toward PROM1 (pGFP-C-shLenti;OriGene, Rockville, MD, USA) were produced by transduction with lentiviral particles, supplemented by 1 μg/mL polybrene. Successful transduction was verified by reverse transcription-quantitative p
FigureFigureFigure
Ultrasound-targeted microbubble destruction-mediated downregulation of CD133 inhibits epithelial-mesenchymal transition, stemness and migratory ability of liver cancer stem cells
Liu, Li, Liu et al
Oncol. Rep. (2015)
Cited by 34
AI Summary: OriGene contributed HuSH 29-mer shRNA constructs against PROM1 (CD133) in the pGFP-V-RS vector, which were used to downregulate CD133 expression and study its effects on liver cancer stem cells in the paper.
Snippet: destruction (UTMD) exposure protocols. The gene-specific short hairpin RNA (shRNA) (HuSH 29-mer shRNA constructs against PROM1 in pGFP-V- RS vector) were obtained from OriGene (Rockville, MD, USA). The cells in ... Cite SaveSaving
Showing 1-2 of 2 papers.
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