Itgam Mouse shRNA Plasmid (Locus ID 16409)
SKU
TL501116
Itgam - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
$1,013.00
In Stock*
Specifications
| Product Data | |
| Locus ID | 16409 |
|---|---|
| Synonyms | Cd11b; CD11b/CD18; CR3; CR3A; F730045J24Rik; Ly-40; Mac-1; Mac-1a; MAC1 |
| Vector | pGFP-C-shLenti |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Lentiviral plasmids |
| Components | Itgam - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 16409). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free. |
| RefSeq | NM_001082960, NM_008401, NM_008401.1, NM_008401.2, NM_001082960.1, BC126892, BC156094, BC156991 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
Reviews
Documents
Resources
Citations
Microglial complement receptor 3 regulates brain Aβ levels through secreted proteolytic activity
Czirr, Castello, Mosher et al
J. Exp. Med. (2017)
Czirr, Castello, Mosher et al
J. Exp. Med. (2017)
AI Summary: OriGene’s CD11b-targeting shRNA lentivirus was used to generate CR3 knockdown microglial cells, enabling the study to investigate how reduced CR3 expression affects Aβ clearance mechanisms.
Snippet: BV2 cells were maintained in DMEM containing 10% FBS. CR3 knockdown (CR3kd) cells were generated by transduction with a CD11b-targeting shRNA lentivirus carrying a puromycin resistance cassette (OriGene) or empty vector control virus. Stable lines were selected with 5 µg/ml puromycin
Showing 1-1 of 1 papers.
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