AXL Human shRNA Plasmid Kit (Locus ID 558)

SKU TL320269

AXL - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided

Product Data

• Locus ID: 558
• Synonyms: ARK; JTK11; Tyro7; UFO
• Vector: pGFP-C-shLenti
• E. coli Selection: Chloramphenicol (34 ug/ml)
• Format: Lentiviral plasmids
• Components: AXL - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 558). 5µg purified plasmid DNA per construct; 29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
• RefSeq: NM_001278599, NM_001699, NM_021913, NM_021913.1, NM_021913.2, NM_021913.3, NM_021913.4, NM_001699.1, NM_001699.2, NM_001699.3, NM_001699.4, NM_001699.5, NM_001278599.1, BC032229, BC032229.1, NM_001699.6, NM_021913.5
• UniProt ID: P30530
• Summary: The protein encoded by this gene is a member of the Tyro3-Axl-Mer (TAM) receptor tyrosine kinase subfamily. The encoded protein possesses an extracellular domain which is composed of two immunoglobulin-like motifs at the N-terminal, followed by two fibronectin type-III motifs. It transduces signals from the extracellular matrix into the cytoplasm by binding to the vitamin K-dependent protein growth arrest-specific 6 (Gas6). This gene may be involved in several cellular functions including growth, migration, aggregation and anti-inflammation in multiple cell types. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jul 2013]
• shRNA Design: These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
• Shipping: Ambient