AXL Human shRNA Plasmid Kit (Locus ID 558)
SKU
TL320269
AXL - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
$1,013.00
In Stock*
Specifications
| Product Data | |
| Locus ID | 558 |
|---|---|
| Synonyms | ARK; JTK11; Tyro7; UFO |
| Vector | pGFP-C-shLenti |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Lentiviral plasmids |
| Components | AXL - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 558). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free. |
| RefSeq | NM_001278599, NM_001699, NM_021913, NM_021913.1, NM_021913.2, NM_021913.3, NM_021913.4, NM_001699.1, NM_001699.2, NM_001699.3, NM_001699.4, NM_001699.5, NM_001278599.1, BC032229, BC032229.1, NM_001699.6, NM_021913.5 |
| UniProt ID | P30530 |
| Summary | The protein encoded by this gene is a member of the Tyro3-Axl-Mer (TAM) receptor tyrosine kinase subfamily. The encoded protein possesses an extracellular domain which is composed of two immunoglobulin-like motifs at the N-terminal, followed by two fibronectin type-III motifs. It transduces signals from the extracellular matrix into the cytoplasm by binding to the vitamin K-dependent protein growth arrest-specific 6 (Gas6). This gene may be involved in several cellular functions including growth, migration, aggregation and anti-inflammation in multiple cell types. Alternative splicing results in multiple transcript variants of this gene. provided by RefSeq, Jul 2013 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
Reviews
Documents
Resources
Citations
Modelling ponatinib resistance in tyrosine kinase inhibitor-naïve and dasatinib resistant BCR-ABL1+ cell lines
Lu, Kok, Saunders et al
Oncotarget (2018) 9 (78), 34735-34747 DOI: 10.18632/oncotarget.26187
Lu, Kok, Saunders et al
Oncotarget (2018) 9 (78), 34735-34747 DOI: 10.18632/oncotarget.26187
Snippet: HEK 293T cells were transfected by lentiviral shRNA plasmid pGFP-C-shLenti comprised of either scramble control vector (sequence as below) or AXL knock-down (sequence as below) with Green Fluorescense Protein (GFP;Origene, MD, USA) according to the manufacturer's instructions. The GFP level and Axl expression level were measured after fluorescence-activated cell sorting (FACS) and before each experiment to ensure purity
Showing 1-2 of 2 papers.
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