EPM2A Human shRNA Plasmid Kit (Locus ID 7957)
Specifications
| Product Data | |
| Locus ID | 7957 |
|---|---|
| Synonyms | EPM2; MELF |
| Vector | pGFP-C-shLenti |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Lentiviral plasmids |
| Components | EPM2A - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 7957). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free. |
| RefSeq | NM_001018041, NM_005670, NM_001360057, NM_001360064, NM_001360071, NR_153397, NR_153398, NM_005670.1, NM_005670.2, NM_005670.3, NM_001018041.1, BC070047, BC070047.1, BC005286, NM_001368132, NM_001368129, NM_001368130, NM_001368131, NM_001018041.2, NM_005670.4 |
| UniProt ID | O95278 |
| Summary | This gene encodes a dual-specificity phosphatase and may be involved in the regulation of glycogen metabolism. The protein acts on complex carbohydrates to prevent glycogen hyperphosphorylation, thus avoiding the formation of insoluble aggregates. Loss-of-function mutations in this gene have been associated with Lafora disease, a rare, adult-onset recessive neurodegenerative disease, which results in myoclonus epilepsy and usually results in death several years after the onset of symptoms. The disease is characterized by the accumulation of insoluble particles called Lafora bodies, which are derived from glycogen. provided by RefSeq, Jan 2018 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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