EPM2A Rabbit Polyclonal Antibody
Specifications
| Product Data | |
| Application | IHC |
|---|---|
| Recommended Dilution | IHC: 50-300 Positive control: Human cervical cancer Predicted cell location: Cytoplasm and Nucleus |
| Reactivity | Human, Mouse, Rat |
| Antibody Host | Rabbit |
| Isotype | IgG |
| Clonality | Polyclonal |
| Immunogen | Fusion protein of human EPM2A |
| Buffer | pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Concentration | lot specific |
| Purification | Antigen affinity purification |
| Conjugation | Unconjugated |
| Storage | Store at -20°C. |
| Stability | 1 year |
| Shipping | Blue Ice |
| Gene Name | epilepsy, progressive myoclonus type 2A, Lafora disease (laforin) |
| Database Link | |
| Background | This gene encodes a dual-specificity phosphatase that associates with polyribosomes. The encoded protein may be involved in the regulation of glycogen metabolism. Mutations in this gene have been associated with myoclonic epilepsy of Lafora. Alternative splicing results in multiple transcript variants. |
| Synonyms | EPM2; laforin; LAFPTPase; LD; LDE; MELF |
| Reference Data | |
| Protein Categories | Intracellular Proteins, Nervous system Diseases |
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