ADAM9 Human shRNA Plasmid Kit (Locus ID 8754)

SKU
TL314947
ADAM9 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
  $1,013.00
In Stock*
Specifications
Specifications
Product Data
Locus ID 8754
Synonyms KIAA0021; MCMP; MDC9; Mltng
Vector pGFP-C-shLenti
E. coli Selection Chloramphenicol (34 ug/ml)
Mammalian Cell Selection Puromycin
Format Lentiviral plasmids
Components ADAM9 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 8754). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
RefSeq BC027996, NM_001005845, NM_003816, NR_027638, NR_027639, NR_027878, NM_003816.1, NM_003816.2, NM_001005845.1, BC126406, BC143923, BC143924, NM_003816.3
UniProt ID Q13443
Summary This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene interacts with SH3 domain-containing proteins, binds mitotic arrest deficient 2 beta protein, and is also involved in TPA-induced ectodomain shedding of membrane-anchored heparin-binding EGF-like growth factor. Several alternatively spliced transcript variants have been identified for this gene. provided by RefSeq, Jul 2010
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
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Documents
Resources

file-alt Citations

Analysis of ADAM9 Regulation and Function in Vestibular Schwannoma Primary Cells
Nattmann, Breun, Monoranu et al
BMC Res Notes (2020) 13 (1), 528 DOI: 10.1186/s13104-020-05378-7
Cited by 4
AI Summary: OriGene products, specifically the Lenti-shRNA particles targeting ADAM9 (TL314947VB) and the Lenti-shRNA Control Particles (TR30021V), were used to achieve ADAM9 knockdown and provide control treatments in vestibular schwannoma primary cell cultures, enabling the study of ADAM9’s regulatory role in tumor cell numbers.
Snippet: Particle TL314947VB (Locus ID 8754) (ADAM9 knock down) or 120 µl Lenti-shRNA Control Particles TR30021V (scrambled control) (all from OriGene, Rockville, MD, USA) and incubated for 2 (Merlin overexpression) or 3 days (shRNA)
Showing 1-1 of 1 papers.
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