BMI1 Human shRNA Plasmid Kit (Locus ID 648)
SKU
TL314462
BMI1 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
$1,013.00
In Stock*
Specifications
| Product Data | |
| Locus ID | 648 |
|---|---|
| Synonyms | flvi-2/bmi-1; FLVI2/BMI1; PCGF4; RNF51 |
| Vector | pGFP-C-shLenti |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Lentiviral plasmids |
| Components | BMI1 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 648). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free. |
| RefSeq | NM_005180, NM_005180.1, NM_005180.2, NM_005180.3, NM_005180.4, NM_005180.5, NM_005180.6, NM_005180.7, NM_005180.8, BC011652, BC011652.2, NM_005180.9 |
| UniProt ID | P35226 |
| Summary | This gene encodes a ring finger protein that is major component of the polycomb group complex 1 (PRC1). This complex functions through chromatin remodeling as an essential epigenetic repressor of multiple regulatory genes involved in embryonic development and self-renewal in somatic stem cells. This protein also plays a central role in DNA damage repair. This gene is an oncogene and aberrant expression is associated with numerous cancers and is associated with resistance to certain chemotherapies. A pseudogene of this gene is found on chromosome X. Read-through transcription also exists between this gene and the upstream COMM domain containing 3 (COMMD3) gene. provided by RefSeq, Sep 2015 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
Reviews
Documents
Resources
Citations
Lens regeneration using endogenous stem cells with gain of visual function
Lin, Ouyang, Zhu et al
Nature (2016) 531 (7594), 323-8 DOI: 10.1038/nature17181
Lin, Ouyang, Zhu et al
Nature (2016) 531 (7594), 323-8 DOI: 10.1038/nature17181
Cited by 206
AI Summary: OriGene products contributed to this study by providing lentiviral shRNA targeting the human BMI1 gene (TL314462) and a shRNA lentiviral packaging kit (TR30022), which were used to investigate the role of BMI1 in lens epithelial cell renewal.
Snippet: Lentiviral shRNA targeting the human BMI1 gene (NCBI Reference Sequence: NM_005180.8) was purchased from Origene (TL314462), ShRNA targeting sequences were as follow: 5′-AATGCCATATTGGTATATGACATAACAGG-3′ and 5′-GTAAGAATCAGATGGCATTATGCTTGTTG-3′. … Lentiviral shRNA particles were prepared using shRNA lentiviral packaging kit (Origene, TR30022). …
Showing 1-1 of 1 papers.
Powered by BizGenius
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
Related Products
- Price:
- Actual Price:
Welcome to OriGene AI!
I'm your AI-powered guide to everything OriGene.
Ask me anything:
- Product specs
- Ordering help
- Technical questions
- How to find exactly what your experiment needs
Prefer a live agent? Connect with us by clicking the green chat icon, as seen in the image below or email our team at custsupport@origene.com.
