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CAD Human shRNA Plasmid Kit (Locus ID 790)

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TL314229
CAD - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
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  $1,013.00
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Specifications
Specifications
Product Data
Locus ID 790
Synonyms CDG1Z; DEE50; EIEE50; GATD4
Vector pGFP-C-shLenti
E. coli Selection Chloramphenicol (34 ug/ml)
Mammalian Cell Selection Puromycin
Format Lentiviral plasmids
Components CAD - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 790). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
RefSeq BC014178, NM_001306079, NM_004341, NM_004341.1, NM_004341.2, NM_004341.3, NM_004341.4, BC065510, BC065510.1, BM927624, NM_004341.5
UniProt ID P27708
Summary The de novo synthesis of pyrimidine nucleotides is required for mammalian cells to proliferate. This gene encodes a trifunctional protein which is associated with the enzymatic activities of the first 3 enzymes in the 6-step pathway of pyrimidine biosynthesis: carbamoylphosphate synthetase (CPS II), aspartate transcarbamoylase, and dihydroorotase. This protein is regulated by the mitogen-activated protein kinase (MAPK) cascade, which indicates a direct link between activation of the MAPK cascade and de novo biosynthesis of pyrimidine nucleotides. Alternative splicing results in multiple transcript variants encoding different isoforms. provided by RefSeq, Apr 2015
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
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