CAD Human shRNA Plasmid Kit (Locus ID 790)
Specifications
| Product Data | |
| Locus ID | 790 |
|---|---|
| Synonyms | CDG1Z; DEE50; EIEE50; GATD4 |
| Vector | pGFP-C-shLenti |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Lentiviral plasmids |
| Components | CAD - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 790). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free. |
| RefSeq | BC014178, NM_001306079, NM_004341, NM_004341.1, NM_004341.2, NM_004341.3, NM_004341.4, BC065510, BC065510.1, BM927624, NM_004341.5 |
| UniProt ID | P27708 |
| Summary | The de novo synthesis of pyrimidine nucleotides is required for mammalian cells to proliferate. This gene encodes a trifunctional protein which is associated with the enzymatic activities of the first 3 enzymes in the 6-step pathway of pyrimidine biosynthesis: carbamoylphosphate synthetase (CPS II), aspartate transcarbamoylase, and dihydroorotase. This protein is regulated by the mitogen-activated protein kinase (MAPK) cascade, which indicates a direct link between activation of the MAPK cascade and de novo biosynthesis of pyrimidine nucleotides. Alternative splicing results in multiple transcript variants encoding different isoforms. provided by RefSeq, Apr 2015 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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