MAL Human shRNA Plasmid Kit (Locus ID 4118)
Specifications
| Product Data | |
| Locus ID | 4118 |
|---|---|
| Synonyms | MVP17; VIP17 |
| Vector | pGFP-C-shLenti |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Lentiviral plasmids |
| Components | MAL - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 4118). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free. |
| RefSeq | NM_002371, NM_022438, NM_022439, NM_022440, NM_002371.1, NM_002371.2, NM_002371.3, NM_022440.1, NM_022440.2, NM_022438.1, NM_022438.2, NM_022439.1, NM_022439.2, BC003006, BC003006.1, BC000458, NM_002371.4 |
| UniProt ID | P21145 |
| Summary | The protein encoded by this gene is a highly hydrophobic integral membrane protein belonging to the MAL family of proteolipids. The protein has been localized to the endoplasmic reticulum of T-cells and is a candidate linker protein in T-cell signal transduction. In addition, this proteolipid is localized in compact myelin of cells in the nervous system and has been implicated in myelin biogenesis and/or function. The protein plays a role in the formation, stabilization and maintenance of glycosphingolipid-enriched membrane microdomains. Down-regulation of this gene has been associated with a variety of human epithelial malignancies. Alternative splicing produces four transcript variants which vary from each other by the presence or absence of alternatively spliced exons 2 and 3. provided by RefSeq, May 2012 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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