KMT2D Human shRNA Plasmid Kit (Locus ID 8085)
SKU
TL311461
KMT2D - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
$1,013.00
In Stock*
Specifications
| Product Data | |
| Locus ID | 8085 |
|---|---|
| Synonyms | AAD10; ALR; CAGL114; KABUK1; KMS; MLL2; MLL4; TNRC21 |
| Vector | pGFP-C-shLenti |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Lentiviral plasmids |
| Components | KMT2D - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 8085). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free. |
| RefSeq | NM_003482, NM_003482.1, NM_003482.2, NM_003482.3, BC039197, BC040663, NM_003482.4 |
| UniProt ID | O14686 |
| Summary | The protein encoded by this gene is a histone methyltransferase that methylates the Lys-4 position of histone H3. The encoded protein is part of a large protein complex called ASCOM, which has been shown to be a transcriptional regulator of the beta-globin and estrogen receptor genes. Mutations in this gene have been shown to be a cause of Kabuki syndrome. provided by RefSeq, Oct 2010 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
Reviews
Documents
Resources
Citations
Grainyhead 1 acts as a drug-inducible conserved transcriptional regulator linked to insulin signaling and lifespan
Grigolon, Araldi, Erni et al
Nat Commun (2022) 13 (1), 107 DOI: 10.1038/s41467-021-27732-4
Grigolon, Araldi, Erni et al
Nat Commun (2022) 13 (1), 107 DOI: 10.1038/s41467-021-27732-4
Cited by 19
AI Summary: OriGene products contributed to this study by providing expression vectors for KMT2D (#TL311461), KDM1A (#TL316984), and PIK3C2A (#TL310432), which were used to investigate the molecular regulation of GRHL1 and its role in insulin signaling and lifespan.
Showing 1-1 of 1 papers.
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