MYBPC3 Human shRNA Plasmid Kit (Locus ID 4607)
Specifications
| Product Data | |
| Locus ID | 4607 |
|---|---|
| Synonyms | CMD1MM; CMH4; cMyBP-C; FHC; LVNC10; MYBP-C |
| Vector | pGFP-C-shLenti |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Lentiviral plasmids |
| Components | MYBPC3 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 4607). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free. |
| RefSeq | NM_000256, NM_000256.1, NM_000256.2, NM_000256.3, BC136543, BC136546, BC142685, BC151211 |
| UniProt ID | Q14896 |
| Summary | MYBPC3 encodes the cardiac isoform of myosin-binding protein C. Myosin-binding protein C is a myosin-associated protein found in the cross-bridge-bearing zone (C region) of A bands in striated muscle. MYBPC3, the cardiac isoform, is expressed exclussively in heart muscle. Regulatory phosphorylation of the cardiac isoform in vivo by cAMP-dependent protein kinase (PKA) upon adrenergic stimulation may be linked to modulation of cardiac contraction. Mutations in MYBPC3 are one cause of familial hypertrophic cardiomyopathy. provided by RefSeq, Jul 2008 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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