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JMJD6 Human shRNA Plasmid Kit (Locus ID 23210)

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SKU
TL310083
JMJD6 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
  $1,013.00
2 Weeks*

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Other products for "JMJD6 or NM_001081461"

Specifications
Specifications
Product Data
Locus ID 23210
Synonyms PSR; PTDSR; PTDSR1
Vector pGFP-C-shLenti
E. coli Selection Chloramphenicol (34 ug/ml)
Mammalian Cell Selection Puromycin
Format Lentiviral plasmids
Components JMJD6 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 23210). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
RefSeq NM_001081461, NM_015167, NM_015167.1, NM_015167.2, NM_001081461.1, BC066654, BC016837, BC047003, NM_001081461.2, NM_015167.3
UniProt ID Q6NYC1
Summary This gene encodes a nuclear protein with a JmjC domain. JmjC domain-containing proteins are predicted to function as protein hydroxylases or histone demethylases. This protein was first identified as a putative phosphatidylserine receptor involved in phagocytosis of apoptotic cells; however, subsequent studies have indicated that it does not directly function in the clearance of apoptotic cells, and questioned whether it is a true phosphatidylserine receptor. Multiple transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, Jul 2008
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
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Documents
Resources

file-alt Citations

Elevated expression of JMJD6 is associated with oral carcinogenesis and maintains cancer stemness properties
Lee, Lee, Rigas et al
Carcinogenesis (2015)
Cited by 65
AI Summary: In this study, OriGene’s pRS JMJD6 shRNA was used to stably knock down JMJD6 expression in oral squamous cell carcinoma cells, enabling the researchers to investigate JMJD6’s role in maintaining cancer stemness properties.
Snippet: functional analyses. JMJD6 was also stably knocked down with lentiviral vectors expressing JMJD6 shRNA (pRS JMJD6shRNA;OriGene). Detailed methods of lentivirus production and infection can be found in our previous publications (24). Infected cells were ... Cite SaveSaving
Showing 1-1 of 1 papers.
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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